Yeast Systems Biology: Model organism and Cell Factory

Jens Nielsen*

*Corresponding author for this work

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For thousands of years the yeast Saccharomyces cerevisiae has served as a cell factory for the production of bread, beer, and wine. In more recent years, this yeast has also served as a cell factory for producing many different fuels, chemicals, food ingredients and pharmaceuticals. S. cerevisiae, however, has also served as a very important model organism for studying eukaryal biology, and even today many new discoveries, important for the treatment of human diseases, are made using this yeast as a model organism. Here I will provide a brief review of the use of S. cerevisiae as a model organism for studying eukaryal biology, its use as a cell factory, and how advances in systems biology underpins developments in both these areas. This article is protected by copyright. All rights reserved.
Original languageEnglish
Article numbere1800421
JournalBiotechnology Journal
Issue number9
Number of pages9
Publication statusPublished - 2019


  • Saccharomyces cerevisiae
  • cell factories
  • metabolic engineering
  • metabolic models
  • synthetic biology

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