Windowless microfluidic platform based on capillary burst valves for high intensity x-ray measurements

Asger Laurberg Vig, Kristoffer Haldrup, Nikolaj Brandt Enevoldsen, Anil Haraksingh Thilsted, Johan Eriksen, Anders Kristensen, Robert Krarup Feidenhans'l, Martin Meedom Nielsen

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    We propose and describe a microfluidic system for high intensity x-ray measurements. The required open access to a microfluidic channel is provided by an out-of-plane capillary burst valve (CBV). The functionality of the out-of-plane CBV is characterized with respect to the diameter of the windowless access hole, ranging from 10 to 130 Am. Maximum driving pressures from 22 to 280 mbar corresponding to refresh rates of the exposed sample from 300 Hz to 54 kHz is demonstrated. The microfluidic system is tested at beamline ID09b at the ESRF synchrotron radiation facility in Grenoble, and x-ray scattering measurements are shown to be feasible and to require only very limited amounts of sample, <1 ml/h of measurements without recapturing of sample. With small adjustments of the present chip design, scattering angles up to 30 can be achieved without shadowing effects and integration on-chip mixing and spectroscopy appears straightforward. (C) 2009 American Institute of Physics.
    Original languageEnglish
    JournalReview of Scientific Instruments
    Issue number11
    Pages (from-to)115114
    Publication statusPublished - 2009

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    Copyright (2009) American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.


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