What do patients in rheumatologic care know about the risks of NSAIDs?

Lykke Ornbjerg, Henning Boje Andersen, Peter Kryger, Bryan Richard Cleal, Merete Lund Hetland

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    Objectives: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used, but have potentially serious adverse effects. We investigated the knowledge of patients with inflammatory arthritis with regards to risks associated with the combination of prescribed and over-the-counter (OTC) NSAIDs, of differences in side effects between acetaminophen and NSAIDs, and from which sources patients received information about side effects.

    Methods: Data from)70 questionnaires provided to consecutive patients with inflammatory arthritis at a rheumatologic outpatient clinic were collected through questionnaires (response rate 75%).

    Results: Eighty-seven percent of patients had taken prescribed NSAIDs or OTC analgesics during the previous 2 weeks, 36% being NSAIDs, and 36% used analgesics regularly. Fifty-four percent would increase the dose of drugs in a bad period, and they were more likely to over-use the OTC drugs than the prescribed drugs (P = 0.002, Mann-Whitney).

    Factors recognized to increase the risk of side effects were: higher dose (81% of patients), long-term treatment (68%), previous side effects (57%), combination of NSAIDs (49%), and old age (31 %). Twenty-three percent assumed that acetaminophen increased the risk of side effects.

    Information was obtained from package inserts (84%), the rheumatologist (80%), and the general practitioner (50%). They had greatest confidence in the rheumatologist, package leaflets, and the general practitioner.

    Conclusion: Incomplete knowledge and misconceptions of some patients suggests that more information on risk factors and side effects to NSAID treatment is needed to improve patient safety. This is especially true about the combination of prescribed and OTC drugs.
    Original languageEnglish
    JournalJournal of Clinical Rheumatology
    Volume14
    Issue number2
    Pages (from-to)69-73
    ISSN1076-1608
    DOIs
    Publication statusPublished - 2008

    Keywords

    • patient education
    • NSAIDs
    • analgesics
    • patient compliance

    Cite this

    Ornbjerg, Lykke ; Andersen, Henning Boje ; Kryger, Peter ; Cleal, Bryan Richard ; Hetland, Merete Lund. / What do patients in rheumatologic care know about the risks of NSAIDs?. In: Journal of Clinical Rheumatology. 2008 ; Vol. 14, No. 2. pp. 69-73.
    @article{b5c86099a59840579c502bc3507e6840,
    title = "What do patients in rheumatologic care know about the risks of NSAIDs?",
    abstract = "Objectives: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used, but have potentially serious adverse effects. We investigated the knowledge of patients with inflammatory arthritis with regards to risks associated with the combination of prescribed and over-the-counter (OTC) NSAIDs, of differences in side effects between acetaminophen and NSAIDs, and from which sources patients received information about side effects. Methods: Data from)70 questionnaires provided to consecutive patients with inflammatory arthritis at a rheumatologic outpatient clinic were collected through questionnaires (response rate 75{\%}). Results: Eighty-seven percent of patients had taken prescribed NSAIDs or OTC analgesics during the previous 2 weeks, 36{\%} being NSAIDs, and 36{\%} used analgesics regularly. Fifty-four percent would increase the dose of drugs in a bad period, and they were more likely to over-use the OTC drugs than the prescribed drugs (P = 0.002, Mann-Whitney). Factors recognized to increase the risk of side effects were: higher dose (81{\%} of patients), long-term treatment (68{\%}), previous side effects (57{\%}), combination of NSAIDs (49{\%}), and old age (31 {\%}). Twenty-three percent assumed that acetaminophen increased the risk of side effects. Information was obtained from package inserts (84{\%}), the rheumatologist (80{\%}), and the general practitioner (50{\%}). They had greatest confidence in the rheumatologist, package leaflets, and the general practitioner. Conclusion: Incomplete knowledge and misconceptions of some patients suggests that more information on risk factors and side effects to NSAID treatment is needed to improve patient safety. This is especially true about the combination of prescribed and OTC drugs.",
    keywords = "patient education, NSAIDs, analgesics, patient compliance",
    author = "Lykke Ornbjerg and Andersen, {Henning Boje} and Peter Kryger and Cleal, {Bryan Richard} and Hetland, {Merete Lund}",
    year = "2008",
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    language = "English",
    volume = "14",
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    What do patients in rheumatologic care know about the risks of NSAIDs? / Ornbjerg, Lykke; Andersen, Henning Boje; Kryger, Peter; Cleal, Bryan Richard; Hetland, Merete Lund.

    In: Journal of Clinical Rheumatology, Vol. 14, No. 2, 2008, p. 69-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

    TY - JOUR

    T1 - What do patients in rheumatologic care know about the risks of NSAIDs?

    AU - Ornbjerg, Lykke

    AU - Andersen, Henning Boje

    AU - Kryger, Peter

    AU - Cleal, Bryan Richard

    AU - Hetland, Merete Lund

    PY - 2008

    Y1 - 2008

    N2 - Objectives: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used, but have potentially serious adverse effects. We investigated the knowledge of patients with inflammatory arthritis with regards to risks associated with the combination of prescribed and over-the-counter (OTC) NSAIDs, of differences in side effects between acetaminophen and NSAIDs, and from which sources patients received information about side effects. Methods: Data from)70 questionnaires provided to consecutive patients with inflammatory arthritis at a rheumatologic outpatient clinic were collected through questionnaires (response rate 75%). Results: Eighty-seven percent of patients had taken prescribed NSAIDs or OTC analgesics during the previous 2 weeks, 36% being NSAIDs, and 36% used analgesics regularly. Fifty-four percent would increase the dose of drugs in a bad period, and they were more likely to over-use the OTC drugs than the prescribed drugs (P = 0.002, Mann-Whitney). Factors recognized to increase the risk of side effects were: higher dose (81% of patients), long-term treatment (68%), previous side effects (57%), combination of NSAIDs (49%), and old age (31 %). Twenty-three percent assumed that acetaminophen increased the risk of side effects. Information was obtained from package inserts (84%), the rheumatologist (80%), and the general practitioner (50%). They had greatest confidence in the rheumatologist, package leaflets, and the general practitioner. Conclusion: Incomplete knowledge and misconceptions of some patients suggests that more information on risk factors and side effects to NSAID treatment is needed to improve patient safety. This is especially true about the combination of prescribed and OTC drugs.

    AB - Objectives: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used, but have potentially serious adverse effects. We investigated the knowledge of patients with inflammatory arthritis with regards to risks associated with the combination of prescribed and over-the-counter (OTC) NSAIDs, of differences in side effects between acetaminophen and NSAIDs, and from which sources patients received information about side effects. Methods: Data from)70 questionnaires provided to consecutive patients with inflammatory arthritis at a rheumatologic outpatient clinic were collected through questionnaires (response rate 75%). Results: Eighty-seven percent of patients had taken prescribed NSAIDs or OTC analgesics during the previous 2 weeks, 36% being NSAIDs, and 36% used analgesics regularly. Fifty-four percent would increase the dose of drugs in a bad period, and they were more likely to over-use the OTC drugs than the prescribed drugs (P = 0.002, Mann-Whitney). Factors recognized to increase the risk of side effects were: higher dose (81% of patients), long-term treatment (68%), previous side effects (57%), combination of NSAIDs (49%), and old age (31 %). Twenty-three percent assumed that acetaminophen increased the risk of side effects. Information was obtained from package inserts (84%), the rheumatologist (80%), and the general practitioner (50%). They had greatest confidence in the rheumatologist, package leaflets, and the general practitioner. Conclusion: Incomplete knowledge and misconceptions of some patients suggests that more information on risk factors and side effects to NSAID treatment is needed to improve patient safety. This is especially true about the combination of prescribed and OTC drugs.

    KW - patient education

    KW - NSAIDs

    KW - analgesics

    KW - patient compliance

    U2 - 10.1097/RHU.0b013e31816b1e8e

    DO - 10.1097/RHU.0b013e31816b1e8e

    M3 - Journal article

    VL - 14

    SP - 69

    EP - 73

    JO - Journal of Clinical Rheumatology

    JF - Journal of Clinical Rheumatology

    SN - 1076-1608

    IS - 2

    ER -