Vesicle incorporating transmembrane protein

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The present invention relates to a vesicle incorporating a transmembrane protein, wherein the vesicle forming material comprises a mixture of poly(ethylene glycol)-block- poly(propylene glycol)-block-poly(ethylene glycol) and polyetheramine. The vesicle according to the invention generally withstand elevated temperature without substantial shrinkage of the diameter, which in turn results in maintenance of the water permeability virtually unaffected. Pluronic based vesicles have a large content of amino groups available on the surface illustrated by the larger zeta potential values available for crosslinking in the polyamide layer by chemical reaction with trimesoyl chloride (TMC).

Original languageEnglish
IPCC08L 71/ 02 A I
Patent numberWO2019081371
Filing date19/10/2018
CountryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date29/08/2018
Priority numberDK2018PA70553
Publication statusPublished - 2 May 2019

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