Vesicle incorporating transmembrane protein

Mariana Spulber (Inventor), Dana Cristina Tvermoes (Inventor), Radoslaw Gorecki (Inventor), Frederik Haugsted (Inventor)

Research output: Patent

34 Downloads (Pure)

Abstract

The present invention relates to a vesicle incorporating a transmembrane protein, wherein the vesicle forming material comprises a mixture of poly(ethylene glycol)-block- poly(propylene glycol)-block-poly(ethylene glycol) and polyetheramine. The vesicle according to the invention generally withstand elevated temperature without substantial shrinkage of the diameter, which in turn results in maintenance of the water permeability virtually unaffected. Pluronic based vesicles have a large content of amino groups available on the surface illustrated by the larger zeta potential values available for crosslinking in the polyamide layer by chemical reaction with trimesoyl chloride (TMC).

Original languageEnglish
IPCC08L 71/ 02 A I
Patent numberWO2019081371
Filing date19/10/2018
CountryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date29/08/2018
Priority numberDK2018PA70553
Publication statusPublished - 2 May 2019

Cite this

Spulber, M., Tvermoes, D. C., Gorecki, R., & Haugsted, F. (2019). IPC No. C08L 71/ 02 A I. Vesicle incorporating transmembrane protein. (Patent No. WO2019081371).
Spulber, Mariana (Inventor) ; Tvermoes, Dana Cristina (Inventor) ; Gorecki, Radoslaw (Inventor) ; Haugsted, Frederik (Inventor). / Vesicle incorporating transmembrane protein. IPC No.: C08L 71/ 02 A I. Patent No.: WO2019081371. Oct 19, 2018.
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abstract = "The present invention relates to a vesicle incorporating a transmembrane protein, wherein the vesicle forming material comprises a mixture of poly(ethylene glycol)-block- poly(propylene glycol)-block-poly(ethylene glycol) and polyetheramine. The vesicle according to the invention generally withstand elevated temperature without substantial shrinkage of the diameter, which in turn results in maintenance of the water permeability virtually unaffected. Pluronic based vesicles have a large content of amino groups available on the surface illustrated by the larger zeta potential values available for crosslinking in the polyamide layer by chemical reaction with trimesoyl chloride (TMC).",
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language = "English",
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Spulber, M, Tvermoes, DC, Gorecki, R & Haugsted, F Oct. 19 2018, Vesicle incorporating transmembrane protein, Patent No. WO2019081371, IPC No. C08L 71/ 02 A I.

Vesicle incorporating transmembrane protein. / Spulber, Mariana (Inventor); Tvermoes, Dana Cristina (Inventor); Gorecki, Radoslaw (Inventor); Haugsted, Frederik (Inventor).

IPC No.: C08L 71/ 02 A I. Patent No.: WO2019081371. Oct 19, 2018.

Research output: Patent

TY - PAT

T1 - Vesicle incorporating transmembrane protein

AU - Spulber, Mariana

AU - Tvermoes, Dana Cristina

AU - Gorecki, Radoslaw

AU - Haugsted, Frederik

PY - 2019/5/2

Y1 - 2019/5/2

N2 - The present invention relates to a vesicle incorporating a transmembrane protein, wherein the vesicle forming material comprises a mixture of poly(ethylene glycol)-block- poly(propylene glycol)-block-poly(ethylene glycol) and polyetheramine. The vesicle according to the invention generally withstand elevated temperature without substantial shrinkage of the diameter, which in turn results in maintenance of the water permeability virtually unaffected. Pluronic based vesicles have a large content of amino groups available on the surface illustrated by the larger zeta potential values available for crosslinking in the polyamide layer by chemical reaction with trimesoyl chloride (TMC).

AB - The present invention relates to a vesicle incorporating a transmembrane protein, wherein the vesicle forming material comprises a mixture of poly(ethylene glycol)-block- poly(propylene glycol)-block-poly(ethylene glycol) and polyetheramine. The vesicle according to the invention generally withstand elevated temperature without substantial shrinkage of the diameter, which in turn results in maintenance of the water permeability virtually unaffected. Pluronic based vesicles have a large content of amino groups available on the surface illustrated by the larger zeta potential values available for crosslinking in the polyamide layer by chemical reaction with trimesoyl chloride (TMC).

M3 - Patent

M1 - WO2019081371

Y2 - 2018/10/19

ER -

Spulber M, Tvermoes DC, Gorecki R, Haugsted F, inventors. Vesicle incorporating transmembrane protein. C08L 71/ 02 A I. 2019 May 2.