Versatile Procedures for the Reliable NMR Quantification of CO2 Electroreduction Products

Allan R.E. Hansen; Kasper Enemark-Rasmussen; Frans A.A. Mulder; Pernille R. Jensen; Sebastian Meier

doi:10.1021/acs.jpcc.2c03448

Versatile Procedures for the Reliable NMR Quantification of CO₂ Electroreduction Products

Allan R.E. Hansen, Kasper Enemark-Rasmussen, Frans A.A. Mulder, Pernille R. Jensen, Sebastian Meier^*

^*Corresponding author for this work

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Abstract

Electrochemical reduction can capture and utilize CO₂ through its conversion to small chemicals and fuels. Analytical standard operating procedures for the accurate quantification of short chain acids, aldehydes, and alcohols by HPLC, GC-MS or NMR are not well established. Electrochemical reduction of CO₂ produces the smallest conceivable organic compounds, which necessitates slow NMR quantifications due to slow T₁ relaxation towards equilibrium magnetization. It is shown that the use of paramagnetic contrast agents or cooling of water/DMSO provides T₁-optimized measurements with attractive sensitivity and speed. ¹H NMR experiments that are widely used in the study of biological mixtures are found unsuitable for quantitative analyses of T₁-optimized samples.

Original language	English
Journal	The Journal of Physical Chemistry Part C
Volume	126
Pages (from-to)	11026-11032
Number of pages	7
ISSN	1932-7447
DOIs	https://doi.org/10.1021/acs.jpcc.2c03448
Publication status	Published - 2022

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abstract = "Electrochemical reduction can capture and utilize CO2 through its conversion to small chemicals and fuels. Analytical standard operating procedures for the accurate quantification of short chain acids, aldehydes, and alcohols by HPLC, GC-MS or NMR are not well established. Electrochemical reduction of CO2 produces the smallest conceivable organic compounds, which necessitates slow NMR quantifications due to slow T1 relaxation towards equilibrium magnetization. It is shown that the use of paramagnetic contrast agents or cooling of water/DMSO provides T1-optimized measurements with attractive sensitivity and speed. 1H NMR experiments that are widely used in the study of biological mixtures are found unsuitable for quantitative analyses of T1-optimized samples.",

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AU - Jensen, Pernille R.

AU - Meier, Sebastian

PY - 2022

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AB - Electrochemical reduction can capture and utilize CO2 through its conversion to small chemicals and fuels. Analytical standard operating procedures for the accurate quantification of short chain acids, aldehydes, and alcohols by HPLC, GC-MS or NMR are not well established. Electrochemical reduction of CO2 produces the smallest conceivable organic compounds, which necessitates slow NMR quantifications due to slow T1 relaxation towards equilibrium magnetization. It is shown that the use of paramagnetic contrast agents or cooling of water/DMSO provides T1-optimized measurements with attractive sensitivity and speed. 1H NMR experiments that are widely used in the study of biological mixtures are found unsuitable for quantitative analyses of T1-optimized samples.

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