Abstract
Described herein are variants of acetylserotonin O-methyltransferase (ASMT) as well as vectors and recombinant microbial host cells expressing such ASMT variant and their use in producing melatonin and related compounds. Preferred ASMT variants provide for a higher turnover of N-acetylserotonin into melatonin.
| Original language | English |
|---|---|
| IPC | C12P 17/ 10 A I |
| Patent number | WO2017202897 |
| Filing date | 30/11/2017 |
| Country/Territory | International Bureau of the World Intellectual Property Organization (WIPO) |
| Priority date | 24/05/2016 |
| Priority number | EP20160171032 |
| Publication status | Published - 30 Nov 2017 |