Validation of Inhibition Effect in the Cellulose Hydrolysis: a Dynamic Modelling Approach

Ricardo Morales Rodriguez, Chien-Tai Tsai, Anne S. Meyer, Krist Gernaey, Gürkan Sin

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Abstract

Enzymatic hydrolysis is one of the main steps in the processing of bioethanol from lignocellulosic raw materials. However, complete understanding of the underlying phenomena is still under development. Hence, this study has focused on validation of the inhibition effects in the cellulosic biomass hydrolysis employing a dynamic mathematical model. A systematic framework for parameter estimation is used for model validation, which helps overcome the problem of parameter correlation. Data sets obtained from carefully designed enzymatic cellulose and cellobiose hydrolysis experiments, were used for parameter estimation (calibration) and validation purposes. The model predictions using calibrated parameters have shown good agreement with the validation data sets, which provides credibility to the model structure and the parameter values.
Original languageEnglish
Title of host publication32. National Meeting and First International Congress AMIDIQ
Publication date2011
Publication statusPublished - 2011
EventAMIDIQ 32nd National Meeting and 1st International Congress - Riviera Maya, Mexico
Duration: 3 May 20116 May 2011

Conference

ConferenceAMIDIQ 32nd National Meeting and 1st International Congress
CountryMexico
CityRiviera Maya
Period03/05/201106/05/2011

Bibliographical note

© 2011 Academia Mexicana de Investigación y Docencia en Ingeniería Química AMIDIQ

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