Utilization and control of ecological interactions in polymicrobial infections and community-based microbial cell factories

Vinoth Wigneswaran, Cristina Isabel Amador Hierro, Lotte Jelsbak, Claus Sternberg, Lars Jelsbak

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    Abstract

    Microbial activities are most often shaped by interactions between co-existing microbes within mixed-species communities. Dissection of the molecular mechanisms of species interactions within communities is a central issue in microbial ecology, and our ability to engineer and control microbial communities depends, to a large extent, on our knowledge of these interactions. This review highlights the recent advances regarding molecular characterization of microbe-microbe interactions that modulate community structure, activity, and stability, and aims to illustrate how these findings have helped us reach an engineering-level understanding of microbial communities in relation to both human health and industrial biotechnology.
    Original languageEnglish
    Article number421
    JournalF1000Research
    Volume5
    Number of pages7
    ISSN2046-1402
    DOIs
    Publication statusPublished - 2016

    Bibliographical note

    © 2016 Wigneswaran V et al. This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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