Use of octaketide synthases to produce kermesic acid and flavokermesic acid

Birger Lindberg  Møller; Bjørn Madsen,; Dan Stærk; Finn Thyge Okkels; Johan Andersen-Ranberg; Kenneth Thermann Kongstad; Kim Binderup; Mads Bennedsen; Majse Nafisi; Paiman Khorsand-Jamal; Rubini Maya Kannangara; Uffe Hasbro Mortensen; Ulf Thrane; Rasmus John Normand Frandsen

Use of octaketide synthases to produce kermesic acid and flavokermesic acid

Birger Lindberg Møller (Inventor), Bjørn Madsen, (Inventor), Dan Stærk (Inventor), Finn Thyge Okkels (Inventor), Johan Andersen-Ranberg (Inventor), Kenneth Thermann Kongstad (Inventor), Kim Binderup (Inventor), Mads Bennedsen (Inventor), Majse Nafisi (Inventor), Paiman Khorsand-Jamal (Inventor), Rubini Maya Kannangara (Inventor), Uffe Hasbro Mortensen (Inventor), Ulf Thrane (Inventor), Rasmus John Normand Frandsen (Inventor)

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Abstract

A method for producing an octaketide derived aromatic compound of interest (e.g. carminic acid), wherein the method comprises (I): heterologous expression of a recombinantly introduced Type III polyketide synthase (PKS) gene encoding an octaketide synthase (OKS) to obtain non-reduced octaketide in vivo within the recombinant host cell and (II): converting in vivo the non-reduced octaketide of step (I) into a C14-C34 aromatic compound of interest (e.g. carminic acid).

Original language	English
IPC	C12P 17/ 06 A I
Patent number	WO2016198564
Filing date	15/12/2016
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	10/06/2015
Priority number	EP20150171375
Publication status	Published - 15 Dec 2016

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Also published as: AU2016277469

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title = "Use of octaketide synthases to produce kermesic acid and flavokermesic acid",

abstract = "A method for producing an octaketide derived aromatic compound of interest (e.g. carminic acid), wherein the method comprises (I): heterologous expression of a recombinantly introduced Type III polyketide synthase (PKS) gene encoding an octaketide synthase (OKS) to obtain non-reduced octaketide in vivo within the recombinant host cell and (II): converting in vivo the non-reduced octaketide of step (I) into a C14-C34 aromatic compound of interest (e.g. carminic acid).",

author = "M{\o}ller, {Birger Lindberg} and Bj{\o}rn Madsen, and Dan St{\ae}rk and Okkels, {Finn Thyge} and Johan Andersen-Ranberg and Kongstad, {Kenneth Thermann} and Kim Binderup and Mads Bennedsen and Majse Nafisi and Paiman Khorsand-Jamal and Kannangara, {Rubini Maya} and Mortensen, {Uffe Hasbro} and Ulf Thrane and Frandsen, {Rasmus John Normand}",

note = "Also published as: AU2016277469; WO2016198564; C12P 17/ 06 A I",

year = "2016",

month = dec,

day = "15",

language = "English",

type = "Patent",

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T1 - Use of octaketide synthases to produce kermesic acid and flavokermesic acid

AU - Møller, Birger Lindberg

AU - Madsen,, Bjørn

AU - Stærk, Dan

AU - Okkels, Finn Thyge

AU - Andersen-Ranberg, Johan

AU - Kongstad, Kenneth Thermann

AU - Binderup, Kim

AU - Bennedsen, Mads

AU - Nafisi, Majse

AU - Khorsand-Jamal, Paiman

AU - Kannangara, Rubini Maya

AU - Mortensen, Uffe Hasbro

AU - Thrane, Ulf

AU - Frandsen, Rasmus John Normand

N1 - Also published as: AU2016277469

PY - 2016/12/15

Y1 - 2016/12/15

N2 - A method for producing an octaketide derived aromatic compound of interest (e.g. carminic acid), wherein the method comprises (I): heterologous expression of a recombinantly introduced Type III polyketide synthase (PKS) gene encoding an octaketide synthase (OKS) to obtain non-reduced octaketide in vivo within the recombinant host cell and (II): converting in vivo the non-reduced octaketide of step (I) into a C14-C34 aromatic compound of interest (e.g. carminic acid).

AB - A method for producing an octaketide derived aromatic compound of interest (e.g. carminic acid), wherein the method comprises (I): heterologous expression of a recombinantly introduced Type III polyketide synthase (PKS) gene encoding an octaketide synthase (OKS) to obtain non-reduced octaketide in vivo within the recombinant host cell and (II): converting in vivo the non-reduced octaketide of step (I) into a C14-C34 aromatic compound of interest (e.g. carminic acid).

M3 - Patent

M1 - WO2016198564

Y2 - 2016/12/15

ER -

Use of octaketide synthases to produce kermesic acid and flavokermesic acid

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