Use of heterologous expressed polyketide synthase and small molecule foldases to make aromatic and cyclic compounds

Rasmus John Normand Frandsen; Uffe Hasbro Mortensen; Hilde Coumou; Rubini Kannangara; Lars Madsen; Majse Nafisi; Johan Andersen Ranberg; Kenneth Thermann Kongstad; Finn T. Okkels; Paiman Khorsand-Jamal; Dan Stærk

Use of heterologous expressed polyketide synthase and small molecule foldases to make aromatic and cyclic compounds

Rasmus John Normand Frandsen (Inventor), Uffe Hasbro Mortensen (Inventor), Hilde Coumou (Inventor), Rubini Kannangara (Inventor), Lars Madsen (Inventor), Majse Nafisi (Inventor), Johan Andersen Ranberg (Inventor), Kenneth Thermann Kongstad (Inventor), Finn T. Okkels (Inventor), Paiman Khorsand-Jamal (Inventor), Dan Stærk (Inventor)

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Abstract

A method for producing individual or libraries of tri- to pentadecaketide-derived aromatic compounds of interest by heterologous expression of polyketide synthase and aromatase/cyclase in a recombinant host cell.

Original language	English
IPC	C12P 19/ 60 A I
Patent number	WO2016198623
Filing date	15/12/2016
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	10/06/2015
Priority number	EP20150171430
Publication status	Published - 15 Dec 2016

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title = "Use of heterologous expressed polyketide synthase and small molecule foldases to make aromatic and cyclic compounds",

abstract = "A method for producing individual or libraries of tri- to pentadecaketide-derived aromatic compounds of interest by heterologous expression of polyketide synthase and aromatase/cyclase in a recombinant host cell.",

author = "Frandsen, {Rasmus John Normand} and Mortensen, {Uffe Hasbro} and Hilde Coumou and Rubini Kannangara and Lars Madsen and Majse Nafisi and Ranberg, {Johan Andersen} and Kongstad, {Kenneth Thermann} and {T. Okkels}, Finn and Paiman Khorsand-Jamal and Dan St{\ae}rk",

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T1 - Use of heterologous expressed polyketide synthase and small molecule foldases to make aromatic and cyclic compounds

AU - Frandsen, Rasmus John Normand

AU - Mortensen, Uffe Hasbro

AU - Coumou, Hilde

AU - Kannangara, Rubini

AU - Madsen, Lars

AU - Nafisi, Majse

AU - Ranberg, Johan Andersen

AU - Kongstad, Kenneth Thermann

AU - T. Okkels, Finn

AU - Khorsand-Jamal, Paiman

AU - Stærk, Dan

PY - 2016/12/15

Y1 - 2016/12/15

N2 - A method for producing individual or libraries of tri- to pentadecaketide-derived aromatic compounds of interest by heterologous expression of polyketide synthase and aromatase/cyclase in a recombinant host cell.

AB - A method for producing individual or libraries of tri- to pentadecaketide-derived aromatic compounds of interest by heterologous expression of polyketide synthase and aromatase/cyclase in a recombinant host cell.

M3 - Patent

M1 - WO2016198623

Y2 - 2016/12/15

ER -

Use of heterologous expressed polyketide synthase and small molecule foldases to make aromatic and cyclic compounds

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