Up-concentration of succinic acid, lactic acid, and ethanol fermentations broths by forward osmosis

Jon Garcia-Aguirre, Merlin Alvarado-Morales, Ioannis Fotidis, Irini Angelidaki*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review


The potential of Forward Osmosis (FO) technology to up-concentrate succinic acid (HSuc), lactic acid (HLac), and ethanol (Eth) from fermentation broths was investigated. The aforementioned molecules were obtained from two residual resources (biopulp and algal biomass) via anaerobic fermentation. HLac and Eth were produced from biopulp and HSuc was produced from macroalgal biomass hydrolysate. Herein, HLac, Eth, and HSuc titers of 14.98 ± 0.76, 19.11 ± 0.51 and 38.8 ± 0.32 g L−1 were obtained respectively. After treatment with centrifugation, FO was applied to the treated broths using a thin film composite hollow fibre (TFHF) membrane. Best results were obtained with the HSuc fermentation broth using NaCl 5.0 M as draw solution. Final HSuc titer of 186.7 ± 9.3 g L−1 and water removal of 85% were attained. Findings in this work highlight a novel application of TFHF membranes.
Original languageEnglish
Article number107482
JournalBiochemical Engineering Journal
Number of pages9
Publication statusPublished - 2019


  • Forward osmosis
  • Hollow fibre membrane
  • Downstream separation
  • Lactic acid
  • Succinic acid, biopulp
  • Saccharina latissima

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