Ultrahigh resolution optical coherence tomography for detecting tissue abnormalities of the oral and laryngeal mucosa: A preliminary study

Niels Møller Israelsen, Mikkel Jensen, Anders Overgård Jønsson, Mette Pedersen

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    Abstract

    Optical coherence tomography (OCT) is an imaging technology that provides cross-sectional images without biopsy of subsurface tissue structure at approximately 10 micrometer resolution to a depth of 1,5 mm using backscattered light from the tissue. OCT has shown promising in imaging normal upper airways and in various disorders. The use of OCT to image the upper airways during diagnosis and treatment of a vast array of disorders continues to develop along with innovative surgical techniques, of patients in anesthesia. Monitoring the benign cellular and molecular events resulting in e.g. edema, in the clinic online is of great interest. There is a need to get information in the clinic about the normal histology of functioning mucosa compared with disorders causing edema especially at the inflammatory process level. The main interesting point is to find out whether it is related to infection, acid reflux, allergy or a fourth condition. Long-range OCT using Doppler OCT is providing useful clinical applications for diagnostic and therapeutic laryngeal procedures of the vocal folds (1). Till now a probe for oral examination of the mucosa with ultrahigh resolution OCT has been established.

    Original languageEnglish
    Title of host publicationProceedings of 11th International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications
    EditorsClaudia Manfredi
    PublisherFirenze University Press
    Publication date2019
    Pages195-198
    ISBN (Electronic)9788864539614
    Publication statusPublished - 2019
    Event11th International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications - Firenze, Italy
    Duration: 17 Dec 201919 Dec 2019

    Conference

    Conference11th International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications
    Country/TerritoryItaly
    CityFirenze
    Period17/12/201919/12/2019

    Keywords

    • In vivo optical coherence tomography
    • Mucosa
    • OCT
    • Upper airways

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