Trichomonas vaginalis surface proteins: a view from the genome

R. P. Hirt, C. J. Noel, Thomas Sicheritz-Pontén, J. Tachezy, P. L. Fiori

    Research output: Contribution to journalJournal articleResearchpeer-review


    Surface proteins of mucosal microbial pathogens play multiple and essential roles in initiating and sustaining the colonization of the heavily defended mucosa. The protist Trichomonas vaginalis is one of the most common human sexually transmitted pathogens that colonize the urogenital mucosa. However, little is known about its surface proteins. The recently completed draft genome sequence of T. vaginalis provides an invaluable resource to guide molecular and cellular characterization of surface proteins and to investigate their role in pathogenicity. Here, we review the existing data on T. vaginalis surface proteins and summarize some of the main findings from the recent in silico characterization of its candidate surface proteins.
    Original languageEnglish
    JournalTrends in parasitology
    Issue number11
    Pages (from-to)540-547
    Publication statusPublished - 2007

    Fingerprint Dive into the research topics of 'Trichomonas vaginalis surface proteins: a view from the genome'. Together they form a unique fingerprint.

    Cite this