Transport or Store? Synthesizing Flow-based Microfluidic Biochips using Distributed Channel Storage

Chunfeng Liu, Bing Li, Hailong Yao, Paul Pop, Tsung-Yi Ho, Ulf Schlichtmann

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review


Flow-based microfluidic biochips have attracted much attention in the EDA community due to their miniaturized size and execution efficiency. Previous research, however, still follows the traditional computing model with a dedicated storage unit, which actually becomes a bottleneck of the performance of biochips. In this paper, we propose the first architectural synthesis framework considering distributed storage constructed temporarily from transportation channels to cache fluid samples. Since distributed storage can be accessed more efficiently than a dedicated storage unit and channels can switch between the roles of transportation and storage easily, biochips with this distributed computing architecture can achieve a higher execution efficiency even with fewer resources. Experimental results confirm that the execution efficiency of a bioassay can be improved by up to 28% while the number of valves in the biochip can be reduced effectively.
Original languageEnglish
Title of host publicationProceedings of the 54th ACM/EDAC/IEEE Design Automation Conference (DAC)
Number of pages6
Publication date2017
ISBN (Electronic)978-1-4503-4927-7
Publication statusPublished - 2017
Event54th ACM/EDAC/IEEE Design Automation Conference - Austin, United States
Duration: 18 Jun 201722 Jun 2017


Conference54th ACM/EDAC/IEEE Design Automation Conference
Country/TerritoryUnited States


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