Roland Wohlgemuth, Mark E.B. Smith, Poul A. Dalby, John Woodley

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review


The enzyme transketolase is a potentially useful catalyst for asymmetric carbon–carbon bond formation. Given the importance of this reaction in organic synthesis, it is not surprising that in recent years there has been particular interest in transketolase. In this review, we describe the background to the reaction, mechanistic and structural information, application in synthesis, and the requirements for larger scale application and implementation.
Original languageEnglish
Title of host publicationEncyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation and Cell Technology
EditorsM.C. Flickinger
Publication date2010
ISBN (Print)9780470054581
Publication statusPublished - 2010


  • Pentose phosphate pathway
  • Organic synthesis


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