Abstract
A practical procedure is reported for the use of the enzyme transketolase, from Escherichia coli, for asymmetric carbon-carbon bond synthesis. The reactions with the biocatalyst are conveniently carried out, on a gram scale, in unbuffered aqueous media by employing a pH autotitrator. An improved large scale synthesis of hydroxypyruvate is also reported.
Original language | English |
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Journal | Tetrahedron Asymmetry |
Volume | 7 |
Pages (from-to) | 2185-2188 |
ISSN | 0957-4166 |
DOIs | |
Publication status | Published - 1996 |
Externally published | Yes |