Abstract
Two separate regimes exist for the aspect ratio of DNA. A low aspect regime where DNA will twist further under strain and a high aspect regime where DNA will untwist under strain. The question of the overall geometry, i.e. the aspect ratio, of DNA is revisited from the perspective of a geometrical analysis of transcription. It is shown that under certain reasonable assumptions transcription is only possible if the aspect ratio is in the regime corresponding to further twisting. We find this constraint to be in agreement with long-established crystallographic studies of DNA.
| Original language | English |
|---|---|
| Article number | 093008 |
| Journal | New Journal of Physics |
| Volume | 15 |
| Issue number | 9 |
| ISSN | 1367-2630 |
| DOIs | |
| Publication status | Published - 2013 |
Bibliographical note
Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence.Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.