Traces of ATCV-1 associated with laboratory component contamination

Kristín Rós Kjartansdóttir, Jens Friis-Nielsen, Maria Asplund, Sarah Mollerup, Tobias Mourier, Randi Holm Jensen, Thomas Arn Hansen, Alba Rey-Iglesia, Stine Raith Richter, David E. Alquezar-Planas, Pernille V. S. Olsen, Lasse Vinner, Helena Fridholm, Thomas Sicheritz-Pontén, Lars Peter Nielsen, Søren Brunak, Eske Willerslev, Jose Maria Gonzalez-Izarzugaza, Anders Johannes Hansen

    Research output: Contribution to journalLetterpeer-review

    Abstract

    Yolken et al. (1) claim detection of Acanthocystis turfacea chlorella virus 1 (ATCV-1, gi119953744) in the normal human oropharyngeal viral flora and associate it with altered cognitive function. However, the reported presence of a freshwater algae virus, previously not known to infect other species, was based on a few sequence reads homologous to ATCV-1 identified with BLASTn. These reads span relatively few bases (97–698 bp) per sample, dispersed over a minor fraction (0.03–0.24%) of the 288 kb ATCV-1 genome.
    Original languageEnglish
    JournalProceedings of the National Academy of Sciences of the United States of America
    Volume112
    Issue number9
    Pages (from-to)E925–E926
    Number of pages2
    ISSN0027-8424
    DOIs
    Publication statusPublished - 2015

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