Abstract
| Original language | English |
|---|---|
| Title of host publication | Proceedings of SPIE |
| Number of pages | 7 |
| Volume | 10890 |
| Publisher | SPIE - International Society for Optical Engineering |
| Publication date | 2019 |
| Article number | 108900W |
| DOIs | |
| Publication status | Published - 2019 |
| Event | Label-free Biomedical Imaging and Sensing 2019 - The Moscone Center, San Francisco, United States Duration: 7 Feb 2019 → 7 Feb 2019 |
Conference
| Conference | Label-free Biomedical Imaging and Sensing 2019 |
|---|---|
| Location | The Moscone Center |
| Country | United States |
| City | San Francisco |
| Period | 07/02/2019 → 07/02/2019 |
| Series | Proceedings of SPIE, the International Society for Optical Engineering |
|---|---|
| Volume | 10890 |
| ISSN | 0277-786X |
Keywords
- Multispectral photoacoustic spectroscopy
- Supercontinuum lasers
- Glucose monitoring
Cite this
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Towards Accurate and Label-free Monitoring of Bio-analytes using Supercontinuum based Multispectral Photoacoustic Spectroscopy in the Extended Near-infrared Wavelength regime. / Dasa, Manoj Kumar; Markos, Christos; Janting, Jakob; Adamu, Abubakar Isa; Bowen, Patrick ; Bang, Ole.
Proceedings of SPIE. Vol. 10890 SPIE - International Society for Optical Engineering, 2019. 108900W (Proceedings of SPIE, the International Society for Optical Engineering, Vol. 10890).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
TY - GEN
T1 - Towards Accurate and Label-free Monitoring of Bio-analytes using Supercontinuum based Multispectral Photoacoustic Spectroscopy in the Extended Near-infrared Wavelength regime
AU - Dasa, Manoj Kumar
AU - Markos, Christos
AU - Janting, Jakob
AU - Adamu, Abubakar Isa
AU - Bowen, Patrick
AU - Bang, Ole
PY - 2019
Y1 - 2019
N2 - In this work, we report a cost-effective supercontinuum (SC) laser-based multispectral photoacoustic spectroscopy (MSPAS) system for studying spectral characteristics of various analytes. We demonstrate an in vitro label-free monitoring of the analytes in the extended near-infrared (NIR) (1540–1840 nm) spectral range. We further demonstrate how a simple ratiometric analysis in conjunction with linear regression can be used for accurate prediction of glucose over commonly encountered physiological levels inside the human body (0–400 mg/dL). Looking forward, the proposed SC-based MSPAS system provides a framework for the development of label-free and non-invasive monitoring multiple bio-analytes accurately, with potential translation to clinical in vivo applications.
AB - In this work, we report a cost-effective supercontinuum (SC) laser-based multispectral photoacoustic spectroscopy (MSPAS) system for studying spectral characteristics of various analytes. We demonstrate an in vitro label-free monitoring of the analytes in the extended near-infrared (NIR) (1540–1840 nm) spectral range. We further demonstrate how a simple ratiometric analysis in conjunction with linear regression can be used for accurate prediction of glucose over commonly encountered physiological levels inside the human body (0–400 mg/dL). Looking forward, the proposed SC-based MSPAS system provides a framework for the development of label-free and non-invasive monitoring multiple bio-analytes accurately, with potential translation to clinical in vivo applications.
KW - Multispectral photoacoustic spectroscopy
KW - Supercontinuum lasers
KW - Glucose monitoring
U2 - 10.1117/12.2510284
DO - 10.1117/12.2510284
M3 - Article in proceedings
VL - 10890
T3 - Proceedings of SPIE, the International Society for Optical Engineering
BT - Proceedings of SPIE
PB - SPIE - International Society for Optical Engineering
ER -