@inproceedings{6d1b64add0104757885294215650a568,
title = "Towards Accurate and Label-free Monitoring of Bio-analytes using Supercontinuum based Multispectral Photoacoustic Spectroscopy in the Extended Near-infrared Wavelength regime",
abstract = "In this work, we report a cost-effective supercontinuum (SC) laser-based multispectral photoacoustic spectroscopy (MSPAS) system for studying spectral characteristics of various analytes. We demonstrate an in vitro label-free monitoring of the analytes in the extended near-infrared (NIR) (1540–1840 nm) spectral range. We further demonstrate how a simple ratiometric analysis in conjunction with linear regression can be used for accurate prediction of glucose over commonly encountered physiological levels inside the human body (0–400 mg/dL). Looking forward, the proposed SC-based MSPAS system provides a framework for the development of label-free and non-invasive monitoring multiple bio-analytes accurately, with potential translation to clinical in vivo applications.",
keywords = "Multispectral photoacoustic spectroscopy, Supercontinuum lasers, Glucose monitoring",
author = "Dasa, {Manoj Kumar} and Christos Markos and Jakob Janting and Adamu, {Abubakar Isa} and Patrick Bowen and Ole Bang",
year = "2019",
doi = "10.1117/12.2510284",
language = "English",
volume = "10890",
series = "Proceedings of SPIE, the International Society for Optical Engineering",
publisher = "SPIE - International Society for Optical Engineering",
booktitle = "Proceedings of SPIE",
note = "Label-free Biomedical Imaging and Sensing 2019, LBIS 2019 ; Conference date: 07-02-2019 Through 07-02-2019",
}