Toward industrial production of isoprenoids in Escherichia coli: Lessons learned from CRISPR-Cas9 based optimization of a chromosomally integrated mevalonate pathway

Jorge Alonso-Gutierrez, Daisuke Koma, Qijun Hu, Yuchen Yang, Leanne J.G. Chan, Christopher J. Petzold, Paul D. Adams, Claudia E. Vickers, Lars K. Nielsen, Jay D. Keasling, Taek S. Lee*

*Corresponding author for this work

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Biochemistry, Genetics and Molecular Biology