Toward Efficient Palladium-Catalyzed Allylic C-H Alkylation

Thomas Jensen, Peter Fristrup

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Recent breakthroughs have proved that direct palladium (II)-catalyzed allylic C-H alkylation can be achieved. This new procedure shows that the inherent requirement for a leaving group in the Tsuji-Trost palladium-catalyzed allylic alkylation can be lifted. These initial reports hold great promise for the development of allylic C-H alkylation into a widely applicable methodology, thus providing a means to enhance synthetic efficiency in these reactions.
Original languageEnglish
JournalChemistry: A European Journal
Volume15
Issue number38
Pages (from-to)9632-9636
ISSN0947-6539
DOIs
Publication statusPublished - 2009

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