This paper describes the construction of three key intermediates for a projected total synthesis of the marine alkaloid zoanthamine. These building blocks, corresponding to the C1-C5, C6-C10 and C11-C24 fragments of the target molecule, are synthesised efficiently form (R)-hydroxymethyl-butyrolactone, methyl propiolate, and (S)-prillyl alcohol, respectively.
|Journal||Acta Chem. Scand.|
|Publication status||Published - 1997|