Thyroid Nodules in an 11-Year DanThyr Follow-Up Study

Anne Krejbjerg; Lena Bjergved; Inge Bulow Pedersen; Nils Knudsen; Torben Jorgensen; Hans Perrild; Lars Ovesen; Lone Banke Rasmussen; Peter Laurberg

doi:10.1210/jc.2014-2438

Thyroid Nodules in an 11-Year DanThyr Follow-Up Study

Anne Krejbjerg, Lena Bjergved, Inge Bulow Pedersen, Nils Knudsen, Torben Jorgensen, Hans Perrild, Lars Ovesen, Lone Banke Rasmussen, Peter Laurberg

National Food Institute

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Context: Limited longitudinal data are available on changes in the thyroid gland structure in a population and how this is influenced by iodine fortification (IF). Objective: Our objective was to clarify how IF influenced thyroid gland structure in 2 regions with different iodine intake at baseline (Copenhagen, mild iodine deficiency [ID]; Aalborg, moderate ID). Design and Setting: We conducted a longitudinal population-based study (DanThyr) where participants were examined before (1997) and after (2008) the Danish mandatory IF of salt (2000). Participants: We examined 2465 adults, and ultrasonography was performed by the same sonographers using the same equipment, after controlling performances. Main Outcome Measure: Change in thyroid gland structure was evaluated. Results: The follow-up period saw an increased prevalence of multinodularity (9.8%-13.8%, P

Original language	English
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	99
Issue number	12
Pages (from-to)	4749-4757
Number of pages	9
ISSN	0021-972X
DOIs	https://doi.org/10.1210/jc.2014-2438
Publication status	Published - 2014

Keywords

ENDOCRINOLOGY
DIFFERENT IODINE STATUS
DEFICIENCY
ULTRASONOGRAPHY
DISORDERS
ABNORMALITIES
THYROGLOBULIN
POPULATIONS
PREVALENCE
REGIONS
VOLUME

Access to Document

10.1210/jc.2014-2438

OpenUrl availability

Full text

Cite this

@article{235bd9c805b74b2e92155044f2111d63,

title = "Thyroid Nodules in an 11-Year DanThyr Follow-Up Study",

abstract = "Context: Limited longitudinal data are available on changes in the thyroid gland structure in a population and how this is influenced by iodine fortification (IF). Objective: Our objective was to clarify how IF influenced thyroid gland structure in 2 regions with different iodine intake at baseline (Copenhagen, mild iodine deficiency [ID]; Aalborg, moderate ID). Design and Setting: We conducted a longitudinal population-based study (DanThyr) where participants were examined before (1997) and after (2008) the Danish mandatory IF of salt (2000). Participants: We examined 2465 adults, and ultrasonography was performed by the same sonographers using the same equipment, after controlling performances. Main Outcome Measure: Change in thyroid gland structure was evaluated. Results: The follow-up period saw an increased prevalence of multinodularity (9.8%-13.8%, P ",

keywords = "ENDOCRINOLOGY, DIFFERENT IODINE STATUS, DEFICIENCY, ULTRASONOGRAPHY, DISORDERS, ABNORMALITIES, THYROGLOBULIN, POPULATIONS, PREVALENCE, REGIONS, VOLUME",

author = "Anne Krejbjerg and Lena Bjergved and Pedersen, {Inge Bulow} and Nils Knudsen and Torben Jorgensen and Hans Perrild and Lars Ovesen and Rasmussen, {Lone Banke} and Peter Laurberg",

year = "2014",

doi = "10.1210/jc.2014-2438",

language = "English",

volume = "99",

pages = "4749--4757",

journal = "Journal of Clinical Endocrinology and Metabolism",

issn = "0021-972X",

publisher = "Oxford University Press",

number = "12",

}

TY - JOUR

T1 - Thyroid Nodules in an 11-Year DanThyr Follow-Up Study

AU - Krejbjerg, Anne

AU - Bjergved, Lena

AU - Pedersen, Inge Bulow

AU - Knudsen, Nils

AU - Jorgensen, Torben

AU - Perrild, Hans

AU - Ovesen, Lars

AU - Rasmussen, Lone Banke

AU - Laurberg, Peter

PY - 2014

Y1 - 2014

N2 - Context: Limited longitudinal data are available on changes in the thyroid gland structure in a population and how this is influenced by iodine fortification (IF). Objective: Our objective was to clarify how IF influenced thyroid gland structure in 2 regions with different iodine intake at baseline (Copenhagen, mild iodine deficiency [ID]; Aalborg, moderate ID). Design and Setting: We conducted a longitudinal population-based study (DanThyr) where participants were examined before (1997) and after (2008) the Danish mandatory IF of salt (2000). Participants: We examined 2465 adults, and ultrasonography was performed by the same sonographers using the same equipment, after controlling performances. Main Outcome Measure: Change in thyroid gland structure was evaluated. Results: The follow-up period saw an increased prevalence of multinodularity (9.8%-13.8%, P

AB - Context: Limited longitudinal data are available on changes in the thyroid gland structure in a population and how this is influenced by iodine fortification (IF). Objective: Our objective was to clarify how IF influenced thyroid gland structure in 2 regions with different iodine intake at baseline (Copenhagen, mild iodine deficiency [ID]; Aalborg, moderate ID). Design and Setting: We conducted a longitudinal population-based study (DanThyr) where participants were examined before (1997) and after (2008) the Danish mandatory IF of salt (2000). Participants: We examined 2465 adults, and ultrasonography was performed by the same sonographers using the same equipment, after controlling performances. Main Outcome Measure: Change in thyroid gland structure was evaluated. Results: The follow-up period saw an increased prevalence of multinodularity (9.8%-13.8%, P

KW - ENDOCRINOLOGY

KW - DIFFERENT IODINE STATUS

KW - DEFICIENCY

KW - ULTRASONOGRAPHY

KW - DISORDERS

KW - ABNORMALITIES

KW - THYROGLOBULIN

KW - POPULATIONS

KW - PREVALENCE

KW - REGIONS

KW - VOLUME

U2 - 10.1210/jc.2014-2438

DO - 10.1210/jc.2014-2438

M3 - Journal article

C2 - 25233154

SN - 0021-972X

VL - 99

SP - 4749

EP - 4757

JO - Journal of Clinical Endocrinology and Metabolism

JF - Journal of Clinical Endocrinology and Metabolism

IS - 12

ER -

Thyroid Nodules in an 11-Year DanThyr Follow-Up Study

Abstract

Keywords

Access to Document

OpenUrl availability

Fingerprint

Cite this