Abstract

A 3-D super resolution (SR) pipeline based on data from a Row-Column (RC) array is presented. The 3 MHz RC array contains 62 rows and 62 columns with a half wavelength pitch. A Synthetic Aperture (SA) pulse inversion sequence with 32 positive and 32 negative row emissions are used for acquiring volumetric data using the SARUS research ultrasound scanner. Data received on the 62 columns are beamformed on a GPU for a maximum volume rate of 156Hz, when the pulse repetition frequency is 10 kHz. Simulated and 3-D printed point and flow micro-phantoms are used for investigating the approach. The flow micro-phantom contains a 100 µm radius tube injected with the contrast agent SonoVue. The 3-D processing pipeline uses the volumetric envelope data to find the bubble’s positions from their interpolated maximum signal and yields a high resolution in all three coordinates. For the point micro-phantom the standard deviation on the position is (20.7,19.8,9.1) µm (x,y,z). The precision estimated for the flow phantom is below 23 µmin all three coordinates, making it possible to locate structures on the order of a capillary in all three dimensions. The RC imaging sequence’s point spread function has a size of 0.58 × 1.05 × 0.31 mm3 (1.17λ×2.12λ×0.63λ), so the possible volume resolution is 28,900 times smaller than for SA RC B-mode imaging.
Original languageEnglish
JournalIEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control
Number of pages11
ISSN0885-3010
DOIs
Publication statusAccepted/In press - 2020

Cite this

@article{41b3c815d22d4f1b8402c5c33f4c15f5,
title = "Three-Dimensional Super Resolution Imaging using a Row-Column Array",
abstract = "A 3-D super resolution (SR) pipeline based on data from a Row-Column (RC) array is presented. The 3 MHz RC array contains 62 rows and 62 columns with a half wavelength pitch. A Synthetic Aperture (SA) pulse inversion sequence with 32 positive and 32 negative row emissions are used for acquiring volumetric data using the SARUS research ultrasound scanner. Data received on the 62 columns are beamformed on a GPU for a maximum volume rate of 156Hz, when the pulse repetition frequency is 10 kHz. Simulated and 3-D printed point and flow micro-phantoms are used for investigating the approach. The flow micro-phantom contains a 100 µm radius tube injected with the contrast agent SonoVue. The 3-D processing pipeline uses the volumetric envelope data to find the bubble’s positions from their interpolated maximum signal and yields a high resolution in all three coordinates. For the point micro-phantom the standard deviation on the position is (20.7,19.8,9.1) µm (x,y,z). The precision estimated for the flow phantom is below 23 µmin all three coordinates, making it possible to locate structures on the order of a capillary in all three dimensions. The RC imaging sequence’s point spread function has a size of 0.58 × 1.05 × 0.31 mm3 (1.17λ×2.12λ×0.63λ), so the possible volume resolution is 28,900 times smaller than for SA RC B-mode imaging.",
author = "Jensen, {J{\o}rgen Arendt} and Ommen, {Martin Lind} and {\O}ygard, {Sigrid Huseb{\o}} and Mikkel Schou and Thomas Sams and Stuart, {Matthias Bo} and Christopher Beers and Thomsen, {Erik Vilain} and Larsen, {Niels Bent} and Tomov, {Borislav Gueorguiev}",
year = "2020",
doi = "10.1109/TUFFC.2019.2948563",
language = "English",
journal = "I E E E Transactions on Ultrasonics, Ferroelectrics and Frequency Control",
issn = "0885-3010",
publisher = "Institute of Electrical and Electronics Engineers",

}

TY - JOUR

T1 - Three-Dimensional Super Resolution Imaging using a Row-Column Array

AU - Jensen, Jørgen Arendt

AU - Ommen, Martin Lind

AU - Øygard, Sigrid Husebø

AU - Schou, Mikkel

AU - Sams, Thomas

AU - Stuart, Matthias Bo

AU - Beers, Christopher

AU - Thomsen, Erik Vilain

AU - Larsen, Niels Bent

AU - Tomov, Borislav Gueorguiev

PY - 2020

Y1 - 2020

N2 - A 3-D super resolution (SR) pipeline based on data from a Row-Column (RC) array is presented. The 3 MHz RC array contains 62 rows and 62 columns with a half wavelength pitch. A Synthetic Aperture (SA) pulse inversion sequence with 32 positive and 32 negative row emissions are used for acquiring volumetric data using the SARUS research ultrasound scanner. Data received on the 62 columns are beamformed on a GPU for a maximum volume rate of 156Hz, when the pulse repetition frequency is 10 kHz. Simulated and 3-D printed point and flow micro-phantoms are used for investigating the approach. The flow micro-phantom contains a 100 µm radius tube injected with the contrast agent SonoVue. The 3-D processing pipeline uses the volumetric envelope data to find the bubble’s positions from their interpolated maximum signal and yields a high resolution in all three coordinates. For the point micro-phantom the standard deviation on the position is (20.7,19.8,9.1) µm (x,y,z). The precision estimated for the flow phantom is below 23 µmin all three coordinates, making it possible to locate structures on the order of a capillary in all three dimensions. The RC imaging sequence’s point spread function has a size of 0.58 × 1.05 × 0.31 mm3 (1.17λ×2.12λ×0.63λ), so the possible volume resolution is 28,900 times smaller than for SA RC B-mode imaging.

AB - A 3-D super resolution (SR) pipeline based on data from a Row-Column (RC) array is presented. The 3 MHz RC array contains 62 rows and 62 columns with a half wavelength pitch. A Synthetic Aperture (SA) pulse inversion sequence with 32 positive and 32 negative row emissions are used for acquiring volumetric data using the SARUS research ultrasound scanner. Data received on the 62 columns are beamformed on a GPU for a maximum volume rate of 156Hz, when the pulse repetition frequency is 10 kHz. Simulated and 3-D printed point and flow micro-phantoms are used for investigating the approach. The flow micro-phantom contains a 100 µm radius tube injected with the contrast agent SonoVue. The 3-D processing pipeline uses the volumetric envelope data to find the bubble’s positions from their interpolated maximum signal and yields a high resolution in all three coordinates. For the point micro-phantom the standard deviation on the position is (20.7,19.8,9.1) µm (x,y,z). The precision estimated for the flow phantom is below 23 µmin all three coordinates, making it possible to locate structures on the order of a capillary in all three dimensions. The RC imaging sequence’s point spread function has a size of 0.58 × 1.05 × 0.31 mm3 (1.17λ×2.12λ×0.63λ), so the possible volume resolution is 28,900 times smaller than for SA RC B-mode imaging.

U2 - 10.1109/TUFFC.2019.2948563

DO - 10.1109/TUFFC.2019.2948563

M3 - Journal article

C2 - 31634831

JO - I E E E Transactions on Ultrasonics, Ferroelectrics and Frequency Control

JF - I E E E Transactions on Ultrasonics, Ferroelectrics and Frequency Control

SN - 0885-3010

ER -