Thiazolidinone prodrugs activated by reactive oxygen species for use in the treatment of inflammatory diseases and cancer

Jorge Peiro Cadahia; Mads Hartvig Clausen; Jon Bondebjerg; Christian Abildgaard Hansen; Nikolaj Sten Andersen

Thiazolidinone prodrugs activated by reactive oxygen species for use in the treatment of inflammatory diseases and cancer

Jorge Peiro Cadahia (Inventor), Mads Hartvig Clausen (Inventor), Jon Bondebjerg (Inventor), Christian Abildgaard Hansen (Inventor), Nikolaj Sten Andersen (Inventor)

Department of Chemistry

Research output: Patent

225 Downloads (Pure)

Abstract

Prodrugs activated predominantly or exclusively in inflammatory tissue, more particularly prodrugs of methotrexate and derivatives thereof, which are selectively activated by Reactive Oxygen Species (ROS) in inflammatory tissues associated with cancer and inflammatory diseases, as well as method for preparing said prodrugs.

Original language	English
IPC	A61K31/519; A61P29/00; A61P35/00; C07D487/04
Patent number	WO2018037119
Filing date	01/03/2018
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	26/08/2016
Priority number	EP20160185889
Publication status	Published - 2018

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

WO2018037119A1Final published version, 1.43 MB

OpenUrl availability

Full text

Cite this

@misc{524db83d1ac04267a578f2d6d1494256,

title = "Thiazolidinone prodrugs activated by reactive oxygen species for use in the treatment of inflammatory diseases and cancer",

abstract = "Prodrugs activated predominantly or exclusively in inflammatory tissue, more particularly prodrugs of methotrexate and derivatives thereof, which are selectively activated by Reactive Oxygen Species (ROS) in inflammatory tissues associated with cancer and inflammatory diseases, as well as method for preparing said prodrugs.",

author = "{Peiro Cadahia}, Jorge and Clausen, {Mads Hartvig} and Jon Bondebjerg and Hansen, {Christian Abildgaard} and Andersen, {Nikolaj Sten}",

year = "2018",

language = "English",

type = "Patent",

note = "WO2018037119; A61K31/519; A61P29/00; A61P35/00; C07D487/04",

}

TY - PAT

T1 - Thiazolidinone prodrugs activated by reactive oxygen species for use in the treatment of inflammatory diseases and cancer

AU - Peiro Cadahia, Jorge

AU - Clausen, Mads Hartvig

AU - Bondebjerg, Jon

AU - Hansen, Christian Abildgaard

AU - Andersen, Nikolaj Sten

PY - 2018

Y1 - 2018

N2 - Prodrugs activated predominantly or exclusively in inflammatory tissue, more particularly prodrugs of methotrexate and derivatives thereof, which are selectively activated by Reactive Oxygen Species (ROS) in inflammatory tissues associated with cancer and inflammatory diseases, as well as method for preparing said prodrugs.

AB - Prodrugs activated predominantly or exclusively in inflammatory tissue, more particularly prodrugs of methotrexate and derivatives thereof, which are selectively activated by Reactive Oxygen Species (ROS) in inflammatory tissues associated with cancer and inflammatory diseases, as well as method for preparing said prodrugs.

M3 - Patent

M1 - WO2018037119

Y2 - 2018/03/01

ER -

Thiazolidinone prodrugs activated by reactive oxygen species for use in the treatment of inflammatory diseases and cancer

Abstract

UN SDGs

Access to Document

OpenUrl availability

Fingerprint

Cite this