The Unrealized Potential of 34mCl for Radiopharmaceutical Research with PET

J. W. Engle, T. E. Barnhart, Gregory W. Severin, R. J. Nickles

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

The unstable isotopes of chlorine have a brief history limited largely to production from sulphur isotopes. Recent improvements in accelerator targetry have made radiochlorine available from small cyclotrons, and concurrent research into labeling chemistry suggests both electrophilic and nucleophilic avenues for the synthesis of novel imaging probes. The prevalence of chlorine compounds from anthropogenic and natural sources offers varied and fertile ground for future scientific explanation with their radiolabeled counterparts.
Original languageEnglish
JournalCurrent Radiopharmaceuticals
Volume4
Issue number2
Pages (from-to)102-108
ISSN1874-4710
DOIs
Publication statusPublished - 2011
Externally publishedYes

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