Abstract
While the use of enzymes as biocatalysts to assist in the industrial manufacture of fine chemicals and pharmaceuticals has enormous potential, application is frequently limited by evolution-led catalyst traits. The advent of designer biocatalysts, produced by informed selection and mutation through recombinant DNA technology, enables production of process-compatible enzymes. However, to fully realize the potential of designer enzymes in industrial applications, it will be necessary to tailor catalyst properties so that they are optimal not only for a given reaction but also in the context of the industrial process in which the enzyme is applied.
Original language | English |
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Journal | Nature Biotechnology |
Volume | 20 |
Issue number | 1 |
Pages (from-to) | 37-45 |
ISSN | 1087-0156 |
DOIs | |
Publication status | Published - 2002 |
Externally published | Yes |