The role of adrenaline as a modulator of cardiac performance in two Antarctic fishes

Peter Vilhelm Skov, Peter G. Bushnell, Bjørn Tirsgaard, John Fleng Steffensen

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

The present work was performed to test the hypothesis that Antarctic teleosts rely mostly on cholinergic inhibition for autonomic modulation of the heart. The effects of adrenaline on the inotropic properties on paced, isometrically contracting muscle strips were examined in two distinct Antarctic teleosts, the haemoglobinless icefish Chaenocephalus aceratus and the red-blooded Notothenia coriiceps. All tissues examined revealed a negative force-frequency relationship. Under baseline conditions C. aceratus contracted with a force twice as great as that of N. coriiceps. While the degree to which ventricular tissues responded to adrenaline varied between species, adrenergic stimulation significantly increases myocyte contraction force in this group of fishes. Contraction and relaxation times were not significantly affected by adrenaline concentration while absolute rates of contraction were. Adrenergic stimulation does not enable tissues to achieve higher contraction frequencies, but is shown to be a potent modulator of contraction force.
Original languageEnglish
JournalPolar Biology
Volume32
Issue number2
Pages (from-to)215-223
ISSN0722-4060
DOIs
Publication statusPublished - 2008
Externally publishedYes

Cite this

Skov, Peter Vilhelm ; Bushnell, Peter G. ; Tirsgaard, Bjørn ; Steffensen, John Fleng. / The role of adrenaline as a modulator of cardiac performance in two Antarctic fishes. In: Polar Biology. 2008 ; Vol. 32, No. 2. pp. 215-223.
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The role of adrenaline as a modulator of cardiac performance in two Antarctic fishes. / Skov, Peter Vilhelm; Bushnell, Peter G.; Tirsgaard, Bjørn; Steffensen, John Fleng.

In: Polar Biology, Vol. 32, No. 2, 2008, p. 215-223.

Research output: Contribution to journalJournal articleResearchpeer-review

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AU - Skov, Peter Vilhelm

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AB - The present work was performed to test the hypothesis that Antarctic teleosts rely mostly on cholinergic inhibition for autonomic modulation of the heart. The effects of adrenaline on the inotropic properties on paced, isometrically contracting muscle strips were examined in two distinct Antarctic teleosts, the haemoglobinless icefish Chaenocephalus aceratus and the red-blooded Notothenia coriiceps. All tissues examined revealed a negative force-frequency relationship. Under baseline conditions C. aceratus contracted with a force twice as great as that of N. coriiceps. While the degree to which ventricular tissues responded to adrenaline varied between species, adrenergic stimulation significantly increases myocyte contraction force in this group of fishes. Contraction and relaxation times were not significantly affected by adrenaline concentration while absolute rates of contraction were. Adrenergic stimulation does not enable tissues to achieve higher contraction frequencies, but is shown to be a potent modulator of contraction force.

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