The next dimension of CAZymes - Inferring the interplay between groups of different CAZy families

Kristian Barrett*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

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Microbial biomass degradation is a huge collaboration exercise for the genome encoded enzymes. Particularly the secreted fiber-active enzymes have an incredibly complicated interplay during which some enzymes may have the direct catalytic effect on the polysaccharides whereas other enzymes may only assist in the conversion indirectly as accessory enzymes. Such accessory enzymes have been greatly overlooked, as the effect is not apparent with the enzyme alone but only in combination with one or more other enzymes. The aim of my work is to identify such putative enzymatic combinations, by systematic identification of co-occurring CAZymes via genome comparisons, to be tested in experimental settings. Thus, unravelling enzyme interplay in microbial biomass conversion while understanding their deployed biological strategies. This method relies on our classification of all CAZy families into functional subgroupings powered by our webserver CUPP.INFO [1].
Original languageEnglish
Title of host publicationDigitally Driven Biotechnology: 4th DTU Bioengineering symposium
Number of pages1
PublisherDTU Bioengineering
Publication date2023
Publication statusPublished - 2023
Event4th DTU Bioengineering symposium - Kgs. Lyngby, Denmark
Duration: 26 Oct 202326 Oct 2023


Conference4th DTU Bioengineering symposium
CityKgs. Lyngby


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