The impact of ultraviolet therapy on stratum corneum ceramides and barrier function

Jakob Mutanu Jungersted; Julie Kaae Høgh; Lars Hellgren; Gregor B. E. Jemec; Tove Agner

doi:10.1111/j.1600-0781.2011.00618.x

The impact of ultraviolet therapy on stratum corneum ceramides and barrier function

Jakob Mutanu Jungersted, Julie Kaae Høgh, Lars Hellgren, Gregor B. E. Jemec, Tove Agner

Copenhagen University Hospital Herlev and Gentofte

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

The ceramide profile as well as the barrier function is known to be deteriorated in atopic eczema and psoriasis, and ultraviolet (UV) light is known to improve the barrier function. The impact of UV light on ceramides, however, is not clarified.The aim of this study was to examine the effect of UV therapy in dermatological patients on ceramides and skin barrier function.We found that UV light treatment does not change the ratio of important stratum corneum lipids, but we confirm earlier findings of decreased susceptibility to irritants after UV- therapy.

Original language	English
Journal	Photodermatology, Photoimmunology & Photomedicine
Volume	27
Pages (from-to)	331-333
ISSN	0905-4383
DOIs	https://doi.org/10.1111/j.1600-0781.2011.00618.x
Publication status	Published - 2011

Keywords

UV light therapy
Ceramides
Skin barrier measurements

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10.1111/j.1600-0781.2011.00618.x

http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0781.2011.00618.x/abstract

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title = "The impact of ultraviolet therapy on stratum corneum ceramides and barrier function",

abstract = "The ceramide profile as well as the barrier function is known to be deteriorated in atopic eczema and psoriasis, and ultraviolet (UV) light is known to improve the barrier function. The impact of UV light on ceramides, however, is not clarified.The aim of this study was to examine the effect of UV therapy in dermatological patients on ceramides and skin barrier function.We found that UV light treatment does not change the ratio of important stratum corneum lipids, but we confirm earlier findings of decreased susceptibility to irritants after UV- therapy.",

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AU - Jungersted, Jakob Mutanu

AU - Høgh, Julie Kaae

AU - Hellgren, Lars

AU - Jemec, Gregor B. E.

AU - Agner, Tove

PY - 2011

Y1 - 2011

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AB - The ceramide profile as well as the barrier function is known to be deteriorated in atopic eczema and psoriasis, and ultraviolet (UV) light is known to improve the barrier function. The impact of UV light on ceramides, however, is not clarified.The aim of this study was to examine the effect of UV therapy in dermatological patients on ceramides and skin barrier function.We found that UV light treatment does not change the ratio of important stratum corneum lipids, but we confirm earlier findings of decreased susceptibility to irritants after UV- therapy.

KW - UV light therapy

KW - Ceramides

KW - Skin barrier measurements

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DO - 10.1111/j.1600-0781.2011.00618.x

M3 - Journal article

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JO - Photodermatology, Photoimmunology & Photomedicine

JF - Photodermatology, Photoimmunology & Photomedicine

ER -

The impact of ultraviolet therapy on stratum corneum ceramides and barrier function

Abstract

Keywords

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