TY - JOUR
T1 - The genomic diversity and stability of field strains of Suid herpesvirus 1 (Aujeszky's disease virus)
AU - Christensen, Laurids Siig
AU - Sørensen, K. J.
PY - 1991
Y1 - 1991
N2 - The genomic diversity among isolates of suid herpesvirus 1 (SHV-1) collected in the same herd and among clones from the same isolate was studied by restriction fragment pattern (RFP) analysis using BamHI. Tentatively defining a field strain as a transmissible entity, it was concluded that strains of SHV-1 commonly comprise distinguishable genomic variants. Contrary to the hypothesis of genomic lability, it is suggested that the pool of variants is sufficiently stable to specifically characterize a strain. The impact of the results on epizootiological methods based on identification of field isolates is discussed in connection with Aujeszky's disease in Denmark.
AB - The genomic diversity among isolates of suid herpesvirus 1 (SHV-1) collected in the same herd and among clones from the same isolate was studied by restriction fragment pattern (RFP) analysis using BamHI. Tentatively defining a field strain as a transmissible entity, it was concluded that strains of SHV-1 commonly comprise distinguishable genomic variants. Contrary to the hypothesis of genomic lability, it is suggested that the pool of variants is sufficiently stable to specifically characterize a strain. The impact of the results on epizootiological methods based on identification of field isolates is discussed in connection with Aujeszky's disease in Denmark.
U2 - 10.1016/0378-1135(91)90037-G
DO - 10.1016/0378-1135(91)90037-G
M3 - Journal article
SN - 0378-1135
VL - 26
SP - 1
EP - 10
JO - Veterinary Microbiology
JF - Veterinary Microbiology
IS - 1-2
ER -