The genomic diversity and stability of field strains of Suid herpesvirus 1 (Aujeszky's disease virus)

Laurids Siig Christensen, K. J. Sørensen

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

The genomic diversity among isolates of suid herpesvirus 1 (SHV-1) collected in the same herd and among clones from the same isolate was studied by restriction fragment pattern (RFP) analysis using BamHI. Tentatively defining a field strain as a transmissible entity, it was concluded that strains of SHV-1 commonly comprise distinguishable genomic variants. Contrary to the hypothesis of genomic lability, it is suggested that the pool of variants is sufficiently stable to specifically characterize a strain. The impact of the results on epizootiological methods based on identification of field isolates is discussed in connection with Aujeszky's disease in Denmark.
Original languageEnglish
JournalVeterinary Microbiology
Volume26
Issue number1-2
Pages (from-to)1-10
ISSN0378-1135
DOIs
Publication statusPublished - 1991

Cite this

Christensen, Laurids Siig ; Sørensen, K. J. / The genomic diversity and stability of field strains of Suid herpesvirus 1 (Aujeszky's disease virus). In: Veterinary Microbiology. 1991 ; Vol. 26, No. 1-2. pp. 1-10.
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The genomic diversity and stability of field strains of Suid herpesvirus 1 (Aujeszky's disease virus). / Christensen, Laurids Siig; Sørensen, K. J.

In: Veterinary Microbiology, Vol. 26, No. 1-2, 1991, p. 1-10.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - The genomic diversity and stability of field strains of Suid herpesvirus 1 (Aujeszky's disease virus)

AU - Christensen, Laurids Siig

AU - Sørensen, K. J.

PY - 1991

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N2 - The genomic diversity among isolates of suid herpesvirus 1 (SHV-1) collected in the same herd and among clones from the same isolate was studied by restriction fragment pattern (RFP) analysis using BamHI. Tentatively defining a field strain as a transmissible entity, it was concluded that strains of SHV-1 commonly comprise distinguishable genomic variants. Contrary to the hypothesis of genomic lability, it is suggested that the pool of variants is sufficiently stable to specifically characterize a strain. The impact of the results on epizootiological methods based on identification of field isolates is discussed in connection with Aujeszky's disease in Denmark.

AB - The genomic diversity among isolates of suid herpesvirus 1 (SHV-1) collected in the same herd and among clones from the same isolate was studied by restriction fragment pattern (RFP) analysis using BamHI. Tentatively defining a field strain as a transmissible entity, it was concluded that strains of SHV-1 commonly comprise distinguishable genomic variants. Contrary to the hypothesis of genomic lability, it is suggested that the pool of variants is sufficiently stable to specifically characterize a strain. The impact of the results on epizootiological methods based on identification of field isolates is discussed in connection with Aujeszky's disease in Denmark.

U2 - 10.1016/0378-1135(91)90037-G

DO - 10.1016/0378-1135(91)90037-G

M3 - Journal article

VL - 26

SP - 1

EP - 10

JO - Veterinary Microbiology

JF - Veterinary Microbiology

SN - 0378-1135

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