The exo-metabolome in filamentous fungi

Ulf Thrane, Birgitte Andersen, Jens Christian Frisvad, Jørn Smedsgaard

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review


Filamentous fungi are a diverse group of eukaryotic microorganisms that have a significant impact on human life as spoilers of food and feed by degradation and toxin production. They are also most useful as a source of bulk and fine chemicals and pharmaceuticals. This chapter focuses on the exo-metabolome in filamentous fungi, which comprises more than 30,000 known secondary metabolites. Profiles of this diverse range of secondary metabolites have, for more than 25 years, been central in development of fungal systematics, taxonomy, and ecology, today integrated in a multidisciplinary and polyphasic approach to applied mycology. Lead discovery is an example of the successful integration of metabolite profiling and natural product chemistry in mycology.
Original languageEnglish
Title of host publicationMetabolomics
Place of PublicationBerlin / Heidelberg
Publication date2007
ISBN (Print)35-40-74718-4
Publication statusPublished - 2007
SeriesTopics in Current Genetics


  • Fungi
  • metabolomics

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