TY - JOUR
T1 - The effect of discontinued use of antimicrobial growth promoters on the risk of therapeutic antibiotic treatment in Danish farrow-to-finish pig farms
AU - Vigre, Håkan
AU - Larsen, P.B.
AU - Andreasen, Morten
AU - Christensen, Julia
AU - Jorsal, Sven Erik Lind
PY - 2008
Y1 - 2008
N2 - This study estimated the effect of discontinued use of antimicrobial growth promoters (duAGPs) oil the risk of antibiotic treatment for diarrhoea, arthritis. pneumonia, unthriving and miscellaneous disorders in Danish pig farms. The estimation was done in a case-crossover study comparing: (1) the proportion of days per farm where treatment was performed (PDT) and (2) the proportion of pigs treated per day per farm at days where treatment was performed (PPT) before and after duAGPs at 68 farrow-to-finish farms. The farms were selected using, a two-stage (veterinarian/farm) convenience sampling. On average, during the first year after duAGPs there was a significant increase in the risk of antibiotic treatment for diarrhoea (PDT: OR 2.5. 95% CI 1.7-3.8; PPT: OR 1.6, 95% CI 1.1-2.2). However, the effect varied among farms - some farms experienced substantial problems, while others experienced few problems after duAGPs. No effect was identified for the risk of treatment for other diseases.
AB - This study estimated the effect of discontinued use of antimicrobial growth promoters (duAGPs) oil the risk of antibiotic treatment for diarrhoea, arthritis. pneumonia, unthriving and miscellaneous disorders in Danish pig farms. The estimation was done in a case-crossover study comparing: (1) the proportion of days per farm where treatment was performed (PDT) and (2) the proportion of pigs treated per day per farm at days where treatment was performed (PPT) before and after duAGPs at 68 farrow-to-finish farms. The farms were selected using, a two-stage (veterinarian/farm) convenience sampling. On average, during the first year after duAGPs there was a significant increase in the risk of antibiotic treatment for diarrhoea (PDT: OR 2.5. 95% CI 1.7-3.8; PPT: OR 1.6, 95% CI 1.1-2.2). However, the effect varied among farms - some farms experienced substantial problems, while others experienced few problems after duAGPs. No effect was identified for the risk of treatment for other diseases.
U2 - 10.1017/S095026880700814X
DO - 10.1017/S095026880700814X
M3 - Journal article
C2 - 17335634
SN - 0950-2688
VL - 136
SP - 92
EP - 107
JO - Epidemiology and Infection
JF - Epidemiology and Infection
IS - 1
ER -
