The effect of amoxicillin-induced intestinal dysbiosis and cholera toxin on gut health and allergic sensitization to cow’s milk – a study in Brown Norway rats

Katrine Bækby Graversen, Arielle Vallee Locke, Martin Iain Bahl, Jeppe Madura Larsen, Tine Rask Licht, Katrine Lindholm Bøgh

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Abstract

Cholera toxin (CT) is a mucosal adjuvant used in animal models of allergy. Some studies have shown that the commensal microbiota is critical for the adjuvant function of CT, but results are conflicting and the mechanism involved remain largely unknown. In the present study, we investigated how CT and dysbiosis induced by the antibiotic amoxicillin (AMX) affect gut health and sensitisation to cow’s milk
Original languageEnglish
Publication date2019
Number of pages1
Publication statusPublished - 2019
Event10th EAACI Pediatric Allergy and Asthma Meeting 2019 - Fortezza da Basso, Florence, Italy
Duration: 17 Oct 201919 Oct 2019
Conference number: 10
https://www.eaaci.org/focused-meetings/paam-2019

Conference

Conference10th EAACI Pediatric Allergy and Asthma Meeting 2019
Number10
LocationFortezza da Basso
CountryItaly
CityFlorence
Period17/10/201919/10/2019
Internet address

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