The effect of amoxicillin-induced intestinal dysbiosis and cholera toxin on gut health and allergic sensitization to cow’s milk – a study in Brown Norway rats

Katrine Bækby Graversen; Arielle Vallee  Locke; Martin Iain Bahl; Jeppe Madura Larsen; Tine Rask Licht; Katrine Lindholm Bøgh

The effect of amoxicillin-induced intestinal dysbiosis and cholera toxin on gut health and allergic sensitization to cow’s milk – a study in Brown Norway rats

Katrine Bækby Graversen, Arielle Vallee Locke, Martin Iain Bahl, Jeppe Madura Larsen, Tine Rask Licht, Katrine Lindholm Bøgh

Technical University of Denmark

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Abstract

Cholera toxin (CT) is a mucosal adjuvant used in animal models of allergy. Some studies have shown that the commensal microbiota is critical for the adjuvant function of CT, but results are conflicting and the mechanism involved remain largely unknown. In the present study, we investigated how CT and dysbiosis induced by the antibiotic amoxicillin (AMX) affect gut health and sensitisation to cow’s milk

Original language	English
Publication date	2019
Number of pages	1
Publication status	Published - 2019
Event	6th EAACI Pediatric Allergy and Asthma Meeting - Fortezza da Basso, Florence, Italy Duration: 17 Oct 2019 → 19 Oct 2019 Conference number: 6 https://eaaci.org/events_meetings/paam-2019/

Conference

Conference	6th EAACI Pediatric Allergy and Asthma Meeting
Number	6
Location	Fortezza da Basso
Country/Territory	Italy
City	Florence
Period	17/10/2019 → 19/10/2019
Internet address	https://eaaci.org/events_meetings/paam-2019/

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The effect of amoxicillin-induced intestinal dysbiosis and cholera toxin on gut health and allergic sensitization to cow’s milk – a study in Brown Norway rat
Katrine Bækby Graversen (Speaker), Arielle Vallee Locke (Other), Martin Iain Bahl (Other), Jeppe Madura Larsen (Other), Tine Rask Licht (Other) & Katrine Lindholm Bøgh (Other)
18 Oct 2019
Activity: Talks and presentations › Conference presentations

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@conference{b007a81154e741d49bfc5f89b252e512,

title = "The effect of amoxicillin-induced intestinal dysbiosis and cholera toxin on gut health and allergic sensitization to cow{\textquoteright}s milk – a study in Brown Norway rats",

abstract = "Cholera toxin (CT) is a mucosal adjuvant used in animal models of allergy. Some studies have shown that the commensal microbiota is critical for the adjuvant function of CT, but results are conflicting and the mechanism involved remain largely unknown. In the present study, we investigated how CT and dysbiosis induced by the antibiotic amoxicillin (AMX) affect gut health and sensitisation to cow{\textquoteright}s milk",

author = "Graversen, {Katrine B{\ae}kby} and Locke, {Arielle Vallee} and Bahl, {Martin Iain} and Larsen, {Jeppe Madura} and Licht, {Tine Rask} and B{\o}gh, {Katrine Lindholm}",

year = "2019",

language = "English",

note = "6th EAACI Pediatric Allergy and Asthma Meeting, PAAM 2019 ; Conference date: 17-10-2019 Through 19-10-2019",

url = "https://eaaci.org/events_meetings/paam-2019/",

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The effect of amoxicillin-induced intestinal dysbiosis and cholera toxin on gut health and allergic sensitization to cow’s milk – a study in Brown Norway rats. / Graversen, Katrine Bækby; Locke, Arielle Vallee ; Bahl, Martin Iain et al.
2019. Abstract from 6th EAACI Pediatric Allergy and Asthma Meeting, Florence, Italy.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

TY - ABST

T1 - The effect of amoxicillin-induced intestinal dysbiosis and cholera toxin on gut health and allergic sensitization to cow’s milk – a study in Brown Norway rats

AU - Graversen, Katrine Bækby

AU - Locke, Arielle Vallee

AU - Bahl, Martin Iain

AU - Larsen, Jeppe Madura

AU - Licht, Tine Rask

AU - Bøgh, Katrine Lindholm

N1 - Conference code: 6

PY - 2019

Y1 - 2019

N2 - Cholera toxin (CT) is a mucosal adjuvant used in animal models of allergy. Some studies have shown that the commensal microbiota is critical for the adjuvant function of CT, but results are conflicting and the mechanism involved remain largely unknown. In the present study, we investigated how CT and dysbiosis induced by the antibiotic amoxicillin (AMX) affect gut health and sensitisation to cow’s milk

AB - Cholera toxin (CT) is a mucosal adjuvant used in animal models of allergy. Some studies have shown that the commensal microbiota is critical for the adjuvant function of CT, but results are conflicting and the mechanism involved remain largely unknown. In the present study, we investigated how CT and dysbiosis induced by the antibiotic amoxicillin (AMX) affect gut health and sensitisation to cow’s milk

M3 - Conference abstract for conference

T2 - 6th EAACI Pediatric Allergy and Asthma Meeting

Y2 - 17 October 2019 through 19 October 2019

ER -

The effect of amoxicillin-induced intestinal dysbiosis and cholera toxin on gut health and allergic sensitization to cow’s milk – a study in Brown Norway rats

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The effect of amoxicillin-induced intestinal dysbiosis and cholera toxin on gut health and allergic sensitization to cow’s milk – a study in Brown Norway rat

Cite this