The effect of a high-protein, high-sodium diet on calcium and bone metabolism in postmenopausal women stratified by hormone replacement therapy use

M. Harrington, T. Bennett, Jette Jakobsen, L. Ovesen, C. Brot, A. Flynn, K. D. Cashman

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

The objective of this study was to investigate the influence of a high-sodium, high-protein diet on bone metabolism in postmenopausal women ( aged 49 - 60 y) stratified by hormone replacement therapy (HRT) use. In a crossover trial, 18 women (n = 8 HRT users (+HRT) and n = 10 nonusers (-HRT)) were randomly assigned to a diet high in protein ( 90 g/day) and sodium (180 mmol/day) ( calciuric diet) or a diet moderate in protein ( 70 g/day) and low in sodium ( 65 mmol/day) for 4 weeks followed by crossover to alternative dietary regimen for a further 4 weeks. The calciuric diet significantly (P
Original languageEnglish
JournalEuropean Journal of Clinical Nutrition
Volume58
Issue number10
Pages (from-to)1436-1439
ISSN0954-3007
Publication statusPublished - 2004

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