The Development of a diagnostic test for the detection of drugs in saliva using a disposable sample preparation Micro-fluidic cartridge

Adama M. Sesay, Ulrich Krühne, Susanna Sonny, Torsten Lund Olesen, Vesa Virtanen

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Abstract

In this paper we report on the development of a diagnostic test for the detection of illegal drugs in saliva using a disposable micro-fluidic sample preparation cartridge which was fabricated using CO2 and excimer laser ablation of a PMMA substrate assembly. The detection method is by immunoassay sensing on a surface plasmon resonance (SPR) platform. Experimental results shows that the immunoassay detection of the two illegal drugs tested are very sensitive and have a linear range for cocaine and MDMA of 0,01 pg/ml – 1 ng/ml and 0,1 pg/ml – 100 ng/ml respectively.
Original languageEnglish
Title of host publicationµTAS 2010 : The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publication date2010
Pages1520-1522
ISBN (Print)978-0-9798064-3-8
Publication statusPublished - 2010
Externally publishedYes
Event14th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Groningen, Netherlands
Duration: 3 Oct 20107 Oct 2010
Conference number: 14

Conference

Conference14th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Number14
CountryNetherlands
CityGroningen
Period03/10/201007/10/2010

Cite this

Sesay, A. M., Krühne, U., Sonny, S., Olesen, T. L., & Virtanen, V. (2010). The Development of a diagnostic test for the detection of drugs in saliva using a disposable sample preparation Micro-fluidic cartridge. In µTAS 2010: The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1520-1522)