Polyethylene glycol in urine samples has been investigated by high performance liquid chromatography. The molecular weights ranged from 634 to 1338. The urine samples were applied to the chromatographic system without any pre-treatment. For samples with a concentration of 0.2% polyethylene glycol a relative standard deviation of 2% was obtained at best. Twenty-six volunteers ingested ten grams of polyethylene glycol and the amount excreted in the urine during the first 6 hours was measured. The recoveries of the individual oligomers were found to be in accordance with those previously published where an extraction procedure was included. The mean recovery was 12.2 .+-. 0.08% for polyethylene glycol with MW = 634 decreasing to 2.1 .+-. 0.3% for MW = 1206.
|Journal||Journal of Trace and Microprobe Techniques|
|Publication status||Published - 1985|