The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China

Yu Deng; Su Hua Guan; Silu Wang; Guiying Hao; Thomas Bruun Rasmussen

doi:10.1155/2018/6216853

The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China

Yu Deng^*, Su Hua Guan, Silu Wang, Guiying Hao, Thomas Bruun Rasmussen

^*Corresponding author for this work

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Abstract

Hepacivirus has been identified in cattle in Africa, Europe, and South America. In this survey of bovine hepacivirus (BovHepV) in 131 serum samples from Chinese cattle herds using RT-PCR, five of 131 sera were BovHepV positive, with the infection rate of 3.82%. Phylogenetic analysis based on the partial NS3 coding sequence showed that the BovHepV of the five positive samples clustered with other BovHepV but formed a separate branch. The results indicated that these new BovHepV represent emerging and novel strains. Further investigations are necessary to determine the epidemiology and viral pathogenesis of these BovHepV strains, as well as the potential threat to ruminant and livestock workers in China.

Original language	English
Article number	6216853
Journal	Journal of Biomedicine and Biotechnology
Volume	2018
Number of pages	4
ISSN	1110-7243
DOIs	https://doi.org/10.1155/2018/6216853
Publication status	Published - 2018

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This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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title = "The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China",

abstract = "Hepacivirus has been identified in cattle in Africa, Europe, and South America. In this survey of bovine hepacivirus (BovHepV) in 131 serum samples from Chinese cattle herds using RT-PCR, five of 131 sera were BovHepV positive, with the infection rate of 3.82%. Phylogenetic analysis based on the partial NS3 coding sequence showed that the BovHepV of the five positive samples clustered with other BovHepV but formed a separate branch. The results indicated that these new BovHepV represent emerging and novel strains. Further investigations are necessary to determine the epidemiology and viral pathogenesis of these BovHepV strains, as well as the potential threat to ruminant and livestock workers in China.",

author = "Yu Deng and Guan, {Su Hua} and Silu Wang and Guiying Hao and Rasmussen, {Thomas Bruun}",

note = "This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.",

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AU - Guan, Su Hua

AU - Wang, Silu

AU - Hao, Guiying

AU - Rasmussen, Thomas Bruun

N1 - This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PY - 2018

Y1 - 2018

N2 - Hepacivirus has been identified in cattle in Africa, Europe, and South America. In this survey of bovine hepacivirus (BovHepV) in 131 serum samples from Chinese cattle herds using RT-PCR, five of 131 sera were BovHepV positive, with the infection rate of 3.82%. Phylogenetic analysis based on the partial NS3 coding sequence showed that the BovHepV of the five positive samples clustered with other BovHepV but formed a separate branch. The results indicated that these new BovHepV represent emerging and novel strains. Further investigations are necessary to determine the epidemiology and viral pathogenesis of these BovHepV strains, as well as the potential threat to ruminant and livestock workers in China.

AB - Hepacivirus has been identified in cattle in Africa, Europe, and South America. In this survey of bovine hepacivirus (BovHepV) in 131 serum samples from Chinese cattle herds using RT-PCR, five of 131 sera were BovHepV positive, with the infection rate of 3.82%. Phylogenetic analysis based on the partial NS3 coding sequence showed that the BovHepV of the five positive samples clustered with other BovHepV but formed a separate branch. The results indicated that these new BovHepV represent emerging and novel strains. Further investigations are necessary to determine the epidemiology and viral pathogenesis of these BovHepV strains, as well as the potential threat to ruminant and livestock workers in China.

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DO - 10.1155/2018/6216853

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JO - Journal of Biomedicine and Biotechnology

JF - Journal of Biomedicine and Biotechnology

M1 - 6216853

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The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China

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