Struktura chemiczna lipopolisacharydu Helicobacter pylori a wrodzona odpowiedź immunologiczna

Translated title of the contribution: The chemical structure of Helicobacter pylori lipopolysaccharide and innate immune response

Michał Arabski, Anna Koza, Wiesław Kaca

Research output: Contribution to journalJournal articleResearch

Abstract

H. pylori is a causative agent of chronic gastritis. Gastrointestinal disorders are associated with a bacterial mechanism of adaptation to the stomach's environment and the immune responses of gastric epithelial cells. The efficacy of H. pylori lipopolysaccharides identify cation by host cells is determined by their chemical structure. This paper focuses mainly on the molecular mechanisms of innate immune evasion by H. pylori, the Toll-like receptor 2/4 activity of epithelial and immune system cells, and molecular mimicry (Lewis antigen).
Translated title of the contributionThe chemical structure of Helicobacter pylori lipopolysaccharide and innate immune response
Original languagePolish
JournalPostepy Higieny i Medycyny Doswiadczalnej
Volume62
Pages (from-to)289-296
ISSN0032-5449
Publication statusPublished - 2008
Externally publishedYes

Keywords

  • Gastric Mucosa
  • Helicobacter pylori
  • Humans
  • Immunity, Innate
  • Lipid A
  • Toll-Like Receptor 2
  • Toll-Like Receptor 4

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