The challenge of detecting classical swine fever virus circulation in wild boar (Sus scrofa): Simulation of sampling options

Jana Schulz, Katja Schulz, Sandra Blome, Christoph Staubach

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    Classical swine fever (CSF) is one of the most important viral diseases of domestic pigs (Sus scrofa domesticus) and wild boar (Sus scrofa). For at least 4 decades, several European Union member states were confronted with outbreaks among wild boar and, as it had been shown that infected wild boar populations can be a major cause of primary outbreaks in domestic pigs, strict control measures for both species were implemented. To guarantee early detection and to demonstrate freedom from disease, intensive surveillance is carried out based on a hunting bag sample. In this context, virologic investigations play a major role in the early detection of new introductions and in regions immunized with a conventional vaccine. The required financial resources and personnel for reliable testing are often large, and sufficient sample sizes to detect low virus prevalences are difficult to obtain. We conducted a simulation to model the possible impact of changes in sample size and sampling intervals on the probability of CSF virus detection based on a study area of 65 German hunting grounds. A 5-yr period with 4,652 virologic investigations was considered. Results suggest that low prevalences could not be detected with a justifiable effort. The simulation of increased sample sizes per sampling interval showed only a slightly better performance but would be unrealistic in practice, especially outside the main hunting season. Further studies on other approaches such as targeted or risk-based sampling for virus detection in connection with (marker) antibody surveillance are needed.
    Original languageEnglish
    JournalJournal of Wildlife Diseases
    Volume52
    Issue number4
    Pages (from-to)828-836
    Number of pages9
    ISSN0090-3558
    DOIs
    Publication statusPublished - 2016

    Keywords

    • Ecology
    • Classical swine fever
    • Sample size
    • Simulation study
    • Surveillance
    • Sus scrofa
    • Wild boar

    Fingerprint Dive into the research topics of 'The challenge of detecting classical swine fever virus circulation in wild boar (Sus scrofa): Simulation of sampling options'. Together they form a unique fingerprint.

    Cite this