The Cancer Epitope Database and Analysis Resource (CEDAR)

Zeynep Kosaloglu-Yalcin; Nina Blazeska; Randi Vita; Hannah Carter; Morten Nielsen; Stephen Schoenberger; Alessandro Sette; Bjoern Peters

doi:10.1093/nar/gkac902

The Cancer Epitope Database and Analysis Resource (CEDAR)

Zeynep Kosaloglu-Yalcin^*
, Nina Blazeska
, Randi Vita
, Hannah Carter
, Morten Nielsen
, Stephen Schoenberger
, Alessandro Sette
, Bjoern Peters

^*Corresponding author for this work

La Jolla Institute for Allergy and Immunology
University of California at San Diego

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

We established The Cancer Epitope Database and Analysis Resource (CEDAR) to catalog all epitope data in the context of cancer. The specific molecular targets of adaptive T cell and B cell immune responses are referred to as epitopes. Epitopes derived from cancer antigens are of high relevance as they are recognized by anti-cancer immune cells. Detailed knowledge of the molecular characteristic of cancer epitopes and associated metadata is relevant to understanding and planning prophylactic and therapeutic applications and accurately characterizing naturally occurring immune responses and cancer immunopathology. CEDAR provides a freely accessible, comprehensive collection of cancer epitope and receptor data curated from the literature and serves as a companion site to the Immune Epitope Database (IEDB), which is focused on infectious, autoimmune, and allergic diseases. CEDAR is freely accessible at https://cedar.iedb.org/.

Original language	English
Article number	gkac902
Journal	Nucleic Acids Research
Volume	51
Issue number	D1
Pages (from-to)	D845–D852
ISSN	0305-1048
DOIs	https://doi.org/10.1093/nar/gkac902
Publication status	Published - 2023

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SDG 3 Good Health and Well-being

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title = "The Cancer Epitope Database and Analysis Resource (CEDAR)",

abstract = "We established The Cancer Epitope Database and Analysis Resource (CEDAR) to catalog all epitope data in the context of cancer. The specific molecular targets of adaptive T cell and B cell immune responses are referred to as epitopes. Epitopes derived from cancer antigens are of high relevance as they are recognized by anti-cancer immune cells. Detailed knowledge of the molecular characteristic of cancer epitopes and associated metadata is relevant to understanding and planning prophylactic and therapeutic applications and accurately characterizing naturally occurring immune responses and cancer immunopathology. CEDAR provides a freely accessible, comprehensive collection of cancer epitope and receptor data curated from the literature and serves as a companion site to the Immune Epitope Database (IEDB), which is focused on infectious, autoimmune, and allergic diseases. CEDAR is freely accessible at https://cedar.iedb.org/.",

author = "Zeynep Kosaloglu-Yalcin and Nina Blazeska and Randi Vita and Hannah Carter and Morten Nielsen and Stephen Schoenberger and Alessandro Sette and Bjoern Peters",

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TY - JOUR

T1 - The Cancer Epitope Database and Analysis Resource (CEDAR)

AU - Kosaloglu-Yalcin, Zeynep

AU - Blazeska, Nina

AU - Vita, Randi

AU - Carter, Hannah

AU - Nielsen, Morten

AU - Schoenberger, Stephen

AU - Sette, Alessandro

AU - Peters, Bjoern

PY - 2023

Y1 - 2023

N2 - We established The Cancer Epitope Database and Analysis Resource (CEDAR) to catalog all epitope data in the context of cancer. The specific molecular targets of adaptive T cell and B cell immune responses are referred to as epitopes. Epitopes derived from cancer antigens are of high relevance as they are recognized by anti-cancer immune cells. Detailed knowledge of the molecular characteristic of cancer epitopes and associated metadata is relevant to understanding and planning prophylactic and therapeutic applications and accurately characterizing naturally occurring immune responses and cancer immunopathology. CEDAR provides a freely accessible, comprehensive collection of cancer epitope and receptor data curated from the literature and serves as a companion site to the Immune Epitope Database (IEDB), which is focused on infectious, autoimmune, and allergic diseases. CEDAR is freely accessible at https://cedar.iedb.org/.

AB - We established The Cancer Epitope Database and Analysis Resource (CEDAR) to catalog all epitope data in the context of cancer. The specific molecular targets of adaptive T cell and B cell immune responses are referred to as epitopes. Epitopes derived from cancer antigens are of high relevance as they are recognized by anti-cancer immune cells. Detailed knowledge of the molecular characteristic of cancer epitopes and associated metadata is relevant to understanding and planning prophylactic and therapeutic applications and accurately characterizing naturally occurring immune responses and cancer immunopathology. CEDAR provides a freely accessible, comprehensive collection of cancer epitope and receptor data curated from the literature and serves as a companion site to the Immune Epitope Database (IEDB), which is focused on infectious, autoimmune, and allergic diseases. CEDAR is freely accessible at https://cedar.iedb.org/.

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DO - 10.1093/nar/gkac902

M3 - Journal article

C2 - 36250634

SN - 0305-1048

VL - 51

SP - D845–D852

JO - Nucleic Acids Research

JF - Nucleic Acids Research

IS - D1

M1 - gkac902

ER -

The Cancer Epitope Database and Analysis Resource (CEDAR)

Abstract

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