The Cancer Epitope Database and Analysis Resource (CEDAR)

Zeynep Kosaloglu-Yalcin; Nina Blazeska; Randi Vita; Hannah Carter; Morten Nielsen; Stephen Schoenberger; Alessandro Sette; Bjoern Peters

doi:10.1093/nar/gkac902

The Cancer Epitope Database and Analysis Resource (CEDAR)

Zeynep Kosaloglu-Yalcin^*, Nina Blazeska, Randi Vita, Hannah Carter, Morten Nielsen, Stephen Schoenberger, Alessandro Sette, Bjoern Peters

^*Corresponding author for this work

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Abstract

We established The Cancer Epitope Database and Analysis Resource (CEDAR) to catalog all epitope data in the context of cancer. The specific molecular targets of adaptive T cell and B cell immune responses are referred to as epitopes. Epitopes derived from cancer antigens are of high relevance as they are recognized by anti-cancer immune cells. Detailed knowledge of the molecular characteristic of cancer epitopes and associated metadata is relevant to understanding and planning prophylactic and therapeutic applications and accurately characterizing naturally occurring immune responses and cancer immunopathology. CEDAR provides a freely accessible, comprehensive collection of cancer epitope and receptor data curated from the literature and serves as a companion site to the Immune Epitope Database (IEDB), which is focused on infectious, autoimmune, and allergic diseases. CEDAR is freely accessible at https://cedar.iedb.org/.

Original language	English
Article number	gkac902
Journal	Nucleic Acids Research
Volume	51
Issue number	D1
Pages (from-to)	D845–D852
ISSN	0305-1048
DOIs	https://doi.org/10.1093/nar/gkac902
Publication status	Published - 2023

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title = "The Cancer Epitope Database and Analysis Resource (CEDAR)",

abstract = "We established The Cancer Epitope Database and Analysis Resource (CEDAR) to catalog all epitope data in the context of cancer. The specific molecular targets of adaptive T cell and B cell immune responses are referred to as epitopes. Epitopes derived from cancer antigens are of high relevance as they are recognized by anti-cancer immune cells. Detailed knowledge of the molecular characteristic of cancer epitopes and associated metadata is relevant to understanding and planning prophylactic and therapeutic applications and accurately characterizing naturally occurring immune responses and cancer immunopathology. CEDAR provides a freely accessible, comprehensive collection of cancer epitope and receptor data curated from the literature and serves as a companion site to the Immune Epitope Database (IEDB), which is focused on infectious, autoimmune, and allergic diseases. CEDAR is freely accessible at https://cedar.iedb.org/.",

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AU - Kosaloglu-Yalcin, Zeynep

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AU - Vita, Randi

AU - Carter, Hannah

AU - Nielsen, Morten

AU - Schoenberger, Stephen

AU - Sette, Alessandro

AU - Peters, Bjoern

PY - 2023

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N2 - We established The Cancer Epitope Database and Analysis Resource (CEDAR) to catalog all epitope data in the context of cancer. The specific molecular targets of adaptive T cell and B cell immune responses are referred to as epitopes. Epitopes derived from cancer antigens are of high relevance as they are recognized by anti-cancer immune cells. Detailed knowledge of the molecular characteristic of cancer epitopes and associated metadata is relevant to understanding and planning prophylactic and therapeutic applications and accurately characterizing naturally occurring immune responses and cancer immunopathology. CEDAR provides a freely accessible, comprehensive collection of cancer epitope and receptor data curated from the literature and serves as a companion site to the Immune Epitope Database (IEDB), which is focused on infectious, autoimmune, and allergic diseases. CEDAR is freely accessible at https://cedar.iedb.org/.

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The Cancer Epitope Database and Analysis Resource (CEDAR)

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