The application of reaction engineering to biocatalysis

Rolf Hoffmeyer Ringborg, John Woodley

Research output: Contribution to journalReviewResearchpeer-review

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Abstract

Biocatalysis is a growing area of synthetic and process chemistry with the ability to deliver not only improved processes for the synthesis of existing compounds, but also new routes to new compounds. In order to assess the many options and strategies available to an engineer developing a new biocatalytic process,it is essential to carry out a systematic evaluation to progress rapidly and ensure decisions are madeon firm foundations. In this way, directed development can be carried out and the chances of implementation of a commercially successful process can be much improved. In this review we outline the benefits of reaction engineering in this development process, with particular emphasis of reaction kinetics. Future research needs to focus on rapid methods to collect such data at sufficient accuracy that it can be used forthe effective design of new biocatalytic processes.
Original languageEnglish
JournalReaction Chemistry & Engineering
Volume1
Pages (from-to)10-22
ISSN2058-9883
DOIs
Publication statusPublished - 2016

Bibliographical note

This article is published Open Access as part of the RSC's Gold for Gold initiative, licensed under a Creative Commons Attribution 3.0 Unported Licence.

Cite this

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abstract = "Biocatalysis is a growing area of synthetic and process chemistry with the ability to deliver not only improved processes for the synthesis of existing compounds, but also new routes to new compounds. In order to assess the many options and strategies available to an engineer developing a new biocatalytic process,it is essential to carry out a systematic evaluation to progress rapidly and ensure decisions are madeon firm foundations. In this way, directed development can be carried out and the chances of implementation of a commercially successful process can be much improved. In this review we outline the benefits of reaction engineering in this development process, with particular emphasis of reaction kinetics. Future research needs to focus on rapid methods to collect such data at sufficient accuracy that it can be used forthe effective design of new biocatalytic processes.",
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The application of reaction engineering to biocatalysis. / Ringborg, Rolf Hoffmeyer; Woodley, John.

In: Reaction Chemistry & Engineering, Vol. 1, 2016, p. 10-22.

Research output: Contribution to journalReviewResearchpeer-review

TY - JOUR

T1 - The application of reaction engineering to biocatalysis

AU - Ringborg, Rolf Hoffmeyer

AU - Woodley, John

N1 - This article is published Open Access as part of the RSC's Gold for Gold initiative, licensed under a Creative Commons Attribution 3.0 Unported Licence.

PY - 2016

Y1 - 2016

N2 - Biocatalysis is a growing area of synthetic and process chemistry with the ability to deliver not only improved processes for the synthesis of existing compounds, but also new routes to new compounds. In order to assess the many options and strategies available to an engineer developing a new biocatalytic process,it is essential to carry out a systematic evaluation to progress rapidly and ensure decisions are madeon firm foundations. In this way, directed development can be carried out and the chances of implementation of a commercially successful process can be much improved. In this review we outline the benefits of reaction engineering in this development process, with particular emphasis of reaction kinetics. Future research needs to focus on rapid methods to collect such data at sufficient accuracy that it can be used forthe effective design of new biocatalytic processes.

AB - Biocatalysis is a growing area of synthetic and process chemistry with the ability to deliver not only improved processes for the synthesis of existing compounds, but also new routes to new compounds. In order to assess the many options and strategies available to an engineer developing a new biocatalytic process,it is essential to carry out a systematic evaluation to progress rapidly and ensure decisions are madeon firm foundations. In this way, directed development can be carried out and the chances of implementation of a commercially successful process can be much improved. In this review we outline the benefits of reaction engineering in this development process, with particular emphasis of reaction kinetics. Future research needs to focus on rapid methods to collect such data at sufficient accuracy that it can be used forthe effective design of new biocatalytic processes.

U2 - 10.1039/C5RE00045A

DO - 10.1039/C5RE00045A

M3 - Review

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