Activities per year
Abstract
Secondary metabolites produced by microorganisms are the main source of bioactive compounds that are in use as antimicrobial and anticancer drugs, fungicides, herbicides and pesticides. In the last decade, the increasing availability of microbial genomes has established genome mining as a very important method for the identification of their biosynthetic gene clusters (BGCs). One of the most popular tools for this task is antiSMASH. However, so far, antiSMASH is limited to de novo computing results for user-submitted genomes and only partially connects these with BGCs from other organisms. Therefore, we developed the antiSMASH database, a simple but highly useful new resource to browse antiSMASH-annotated BGCs in the currently 3907 bacterial genomes in the database and perform advanced search queries combining multiple search criteria. antiSMASH-DB is available at http://antismash-db.secondarymetabolites.org/.
Original language | English |
---|---|
Journal | Nucleic Acids Research |
Volume | 45 |
Issue number | D1 |
Pages (from-to) | D555-D559 |
Number of pages | 5 |
ISSN | 0305-1048 |
DOIs | |
Publication status | Published - 2017 |
Bibliographical note
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.Fingerprint
Dive into the research topics of 'The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters'. Together they form a unique fingerprint.-
The next generation of 'omics-based natural products discovery
Tilmann Weber (Invited speaker)
20 Jan 2017Activity: Talks and presentations › Conference presentations
-
3rd antiSMASH Hackathon
Tilmann Weber (Organizer)
8 Nov 2016 → 9 Nov 2016Activity: Attending an event › Participating in or organising a conference