Abstract
Large numbers of tumor associated antigens has been characterized, but only a minor fraction of these are recognized by tumor infiltrating lymphocytes of melanoma, although these have shown the ability to recognize tumor and provide tumor regression upon adoptive transfer. Thus the peptide recognition of the majority of the CD8 tumor infiltrating lymphocytes remains to be identified.
| Original language | English |
|---|---|
| Journal | OncoImmunology |
| Volume | 1 |
| Issue number | 6 |
| Pages (from-to) | 935-936 |
| Number of pages | 2 |
| ISSN | 2162-4011 |
| DOIs | |
| Publication status | Published - 2012 |
| Externally published | Yes |
Keywords
- Immunology and Allergy
- Oncology
- Immunology
- Antigens
- CD8 T cells
- Melanoma
- T-cell epitopes
- Tumor infiltrating lymphocytes
- CD8 antigen
- epitope
- HLA A2 antigen
- tumor antigen
- adoptive transfer
- antigen recognition
- article
- CD8+ T lymphocyte
- chemical composition
- human
- melanoma
- priority journal
- tumor associated leukocyte
- tumor immunity
- tumor regression
- ONCOLOGY
- IMMUNOLOGY
- MULTIMERS
- tumor infiltrating lymphocytes
- antigens
- peptide recognition
- melanoma Melanoma (MeSH) neoplastic disease, integumentary system disease
- Primates Mammalia Vertebrata Chordata Animalia (Animals, Chordates, Humans, Mammals, Primates, Vertebrates) - Hominidae [86215] human common
- tumor associated antigen
- 15002, Blood - Blood and lymph studies
- 15004, Blood - Blood cell studies
- 18506, Integumentary system - Pathology
- 24003, Neoplasms - Immunology
- 24004, Neoplasms - Pathology, clinical aspects and systemic effects
- 34502, Immunology - General and methods
- 34508, Immunology - Immunopathology, tissue immunology
- Human Medicine, Medical Sciences
- CD8 tumor-infiltrating lymphocyte immune system, blood and lymphatics
- Clinical Immunology
- Dermatology
