The Angioarchitecture of the Optic Nerve Head in Patients with Optic Disc Drusen

Julie Vahlgren; Lasse Malmqvist; Lea Lybæk Rueløkke; Isabelle Karlesand; Anne-Sofie Wessel Lindberg; Steffen Hamann

doi:10.1080/01658107.2019.1613666

The Angioarchitecture of the Optic Nerve Head in Patients with Optic Disc Drusen

Julie Vahlgren, Lasse Malmqvist, Lea Lybæk Rueløkke, Isabelle Karlesand, Anne-Sofie Wessel Lindberg, Steffen Hamann

University of Copenhagen

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Abstract

The aim was to analyse the optic disc angioarchitecture in optic disc drusen (ODD) patients using computer-based fundus analysis in a case–control study. Compared with controls the ODD group had a significantly more centralised central retinal artery (CRA) emergence (p <0.001) and primary CRA branching (p = 0.008), a higher number of CRA bifurcations (p = 0.02), a larger vertical optic disc diameter (p = 0.02) and a smaller cup/disc ratio (p <0.001). The CRA emergence was largely within the nasal zone for both groups. The distinctive angioarchitecture of the optic disc in ODD patients can play a role in understanding the pathogenic cause of ODD.

Original language	English
Journal	Journal of Neuro-Ophthalmology
Volume	44
Issue number	1
Pages (from-to)	5-10
ISSN	1070-8022
DOIs	https://doi.org/10.1080/01658107.2019.1613666
Publication status	Published - 2019

Keywords

Optic disc drusen
Optic nerve head drusen
Optic nerve head microvasculature
Optic nerve head angioarchitecture

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10.1080/01658107.2019.1613666

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abstract = "The aim was to analyse the optic disc angioarchitecture in optic disc drusen (ODD) patients using computer-based fundus analysis in a case–control study. Compared with controls the ODD group had a significantly more centralised central retinal artery (CRA) emergence (p <0.001) and primary CRA branching (p = 0.008), a higher number of CRA bifurcations (p = 0.02), a larger vertical optic disc diameter (p = 0.02) and a smaller cup/disc ratio (p <0.001). The CRA emergence was largely within the nasal zone for both groups. The distinctive angioarchitecture of the optic disc in ODD patients can play a role in understanding the pathogenic cause of ODD.",

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AU - Vahlgren, Julie

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AU - Karlesand, Isabelle

AU - Lindberg, Anne-Sofie Wessel

AU - Hamann, Steffen

PY - 2019

Y1 - 2019

N2 - The aim was to analyse the optic disc angioarchitecture in optic disc drusen (ODD) patients using computer-based fundus analysis in a case–control study. Compared with controls the ODD group had a significantly more centralised central retinal artery (CRA) emergence (p <0.001) and primary CRA branching (p = 0.008), a higher number of CRA bifurcations (p = 0.02), a larger vertical optic disc diameter (p = 0.02) and a smaller cup/disc ratio (p <0.001). The CRA emergence was largely within the nasal zone for both groups. The distinctive angioarchitecture of the optic disc in ODD patients can play a role in understanding the pathogenic cause of ODD.

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KW - Optic nerve head drusen

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The Angioarchitecture of the Optic Nerve Head in Patients with Optic Disc Drusen

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