The Angioarchitecture of the Optic Nerve Head in Patients with Optic Disc Drusen

Julie Vahlgren, Lasse Malmqvist, Lea Lybæk Rueløkke, Isabelle Karlesand, Anne-Sofie Wessel Lindberg, Steffen Hamann

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Abstract

The aim was to analyse the optic disc angioarchitecture in optic disc drusen (ODD) patients using computer-based fundus analysis in a case–control study. Compared with controls the ODD group had a significantly more centralised central retinal artery (CRA) emergence (p <0.001) and primary CRA branching (p = 0.008), a higher number of CRA bifurcations (p = 0.02), a larger vertical optic disc diameter (p = 0.02) and a smaller cup/disc ratio (p <0.001). The CRA emergence was largely within the nasal zone for both groups. The distinctive angioarchitecture of the optic disc in ODD patients can play a role in understanding the pathogenic cause of ODD.
Original languageEnglish
JournalJournal of Neuro-Ophthalmology
Volume44
Issue number1
Pages (from-to)5-10
ISSN1070-8022
DOIs
Publication statusPublished - 2019

Keywords

  • Optic disc drusen
  • Optic nerve head drusen
  • Optic nerve head microvasculature
  • Optic nerve head angioarchitecture

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