Temperature-Controlled High-Throughput (1 L/H) Acoustophoretic Particle Separation In Microchannels

C. L. Ebbesen, J. D. Adams, Rune Barnkob, H. T. Soh, Henrik Bruus

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    Abstract

    We present a microfluidic acoustophoretic separator capable of unprecedented high throughput (about 1 L/h for a whole blood sample), approximately hundred times higher than previously reported. The high throughput along the x direction in the broad and shallow channel is facilitated by a large width (17 mm) in the y direction and a standing ultrasound wave in the shallow (830 μm) z direction. The necessary high acoustic power is obtained by running the attached piezo transducer at 55 V while keeping it cooled with a Peltier element. The device is fabricated using low-cost rapid-prototyping techniques, facilitating easy and versatile application.
    Original languageEnglish
    Title of host publicationProceeding of the 14. International Conference on Miniaturized Systems for Chemistry and Life Sciences
    Publication date2010
    Pages728-730
    Publication statusPublished - 2010
    Event14th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Groningen, Netherlands
    Duration: 3 Oct 20107 Oct 2010
    Conference number: 14

    Conference

    Conference14th International Conference on Miniaturized Systems for Chemistry and Life Sciences
    Number14
    CountryNetherlands
    CityGroningen
    Period03/10/201007/10/2010

    Keywords

    • High-throughput on-chip separation
    • Cell handling
    • Acoustophoresis
    • Blood separation

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