Temperature-Controlled High-Throughput (1 L/H) Acoustophoretic Particle Separation In Microchannels

C. L. Ebbesen; J. D. Adams; Rune Barnkob; H. T. Soh; Henrik Bruus

Temperature-Controlled High-Throughput (1 L/H) Acoustophoretic Particle Separation In Microchannels

C. L. Ebbesen, J. D. Adams, Rune Barnkob, H. T. Soh, Henrik Bruus

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

Abstract

We present a microfluidic acoustophoretic separator capable of unprecedented high throughput (about 1 L/h for a whole blood sample), approximately hundred times higher than previously reported. The high throughput along the x direction in the broad and shallow channel is facilitated by a large width (17 mm) in the y direction and a standing ultrasound wave in the shallow (830 μm) z direction. The necessary high acoustic power is obtained by running the attached piezo transducer at 55 V while keeping it cooled with a Peltier element. The device is fabricated using low-cost rapid-prototyping techniques, facilitating easy and versatile application.

Original language	English
Title of host publication	Proceeding of the 14. International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publication date	2010
Pages	728-730
Publication status	Published - 2010
Event	14th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Groningen, Netherlands Duration: 3 Oct 2010 → 7 Oct 2010 Conference number: 14 https://microtasconferences.org/microtas2010/

Conference

Conference	14th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Number	14
Country/Territory	Netherlands
City	Groningen
Period	03/10/2010 → 07/10/2010
Internet address	https://microtasconferences.org/microtas2010/

Keywords

High-throughput on-chip separation
Cell handling
Acoustophoresis
Blood separation

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title = "Temperature-Controlled High-Throughput (1 L/H) Acoustophoretic Particle Separation In Microchannels",

abstract = "We present a microfluidic acoustophoretic separator capable of unprecedented high throughput (about 1 L/h for a whole blood sample), approximately hundred times higher than previously reported. The high throughput along the x direction in the broad and shallow channel is facilitated by a large width (17 mm) in the y direction and a standing ultrasound wave in the shallow (830 μm) z direction. The necessary high acoustic power is obtained by running the attached piezo transducer at 55 V while keeping it cooled with a Peltier element. The device is fabricated using low-cost rapid-prototyping techniques, facilitating easy and versatile application.",

keywords = "High-throughput on-chip separation, Cell handling, Acoustophoresis, Blood separation",

author = "Ebbesen, {C. L.} and Adams, {J. D.} and Rune Barnkob and Soh, {H. T.} and Henrik Bruus",

year = "2010",

language = "English",

pages = "728--730",

booktitle = "Proceeding of the 14. International Conference on Miniaturized Systems for Chemistry and Life Sciences",

note = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2010 ; Conference date: 03-10-2010 Through 07-10-2010",

url = "https://microtasconferences.org/microtas2010/",

}

Ebbesen, CL, Adams, JD, Barnkob, R, Soh, HT & Bruus, H 2010, Temperature-Controlled High-Throughput (1 L/H) Acoustophoretic Particle Separation In Microchannels. in Proceeding of the 14. International Conference on Miniaturized Systems for Chemistry and Life Sciences. pp. 728-730, 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Groningen, Netherlands, 03/10/2010. <http://www.microtas10.org/>

Temperature-Controlled High-Throughput (1 L/H) Acoustophoretic Particle Separation In Microchannels. / Ebbesen, C. L.; Adams, J. D.; Barnkob, Rune et al.
Proceeding of the 14. International Conference on Miniaturized Systems for Chemistry and Life Sciences. 2010. p. 728-730.

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

TY - GEN

T1 - Temperature-Controlled High-Throughput (1 L/H) Acoustophoretic Particle Separation In Microchannels

AU - Ebbesen, C. L.

AU - Adams, J. D.

AU - Barnkob, Rune

AU - Soh, H. T.

AU - Bruus, Henrik

N1 - Conference code: 14

PY - 2010

Y1 - 2010

N2 - We present a microfluidic acoustophoretic separator capable of unprecedented high throughput (about 1 L/h for a whole blood sample), approximately hundred times higher than previously reported. The high throughput along the x direction in the broad and shallow channel is facilitated by a large width (17 mm) in the y direction and a standing ultrasound wave in the shallow (830 μm) z direction. The necessary high acoustic power is obtained by running the attached piezo transducer at 55 V while keeping it cooled with a Peltier element. The device is fabricated using low-cost rapid-prototyping techniques, facilitating easy and versatile application.

AB - We present a microfluidic acoustophoretic separator capable of unprecedented high throughput (about 1 L/h for a whole blood sample), approximately hundred times higher than previously reported. The high throughput along the x direction in the broad and shallow channel is facilitated by a large width (17 mm) in the y direction and a standing ultrasound wave in the shallow (830 μm) z direction. The necessary high acoustic power is obtained by running the attached piezo transducer at 55 V while keeping it cooled with a Peltier element. The device is fabricated using low-cost rapid-prototyping techniques, facilitating easy and versatile application.

KW - High-throughput on-chip separation

KW - Cell handling

KW - Acoustophoresis

KW - Blood separation

M3 - Article in proceedings

SP - 728

EP - 730

BT - Proceeding of the 14. International Conference on Miniaturized Systems for Chemistry and Life Sciences

T2 - 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Y2 - 3 October 2010 through 7 October 2010

ER -

Temperature-Controlled High-Throughput (1 L/H) Acoustophoretic Particle Separation In Microchannels

Abstract

Conference

Keywords

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