@article{608c1fa66d8b4d6a976f95e643ba8ce5,
title = "Targeted delivery of alcohol-containing payloads with antibody-drug conjugates",
abstract = "We herein describe the cell-specific release of alcohol-containing payloads via a sulfatase-sensitive linker in antibody-drug conjugates (ADCs). The linker shows efficient sulfatase-mediated release and high stability in human and mouse plasma. In vitro evaluation demonstrates potent antigen dependent toxicity towards breast cancer cell lines.",
author = "Grier, {Katja E.} and Hansen, {Anders H.} and Haxvig, {Christina S.} and Xin Li and Oliver Krigslund and Niels Behrendt and Engelholm, {Lars H.} and Fabio Rossi and Sousa, {Bebiana C.} and Harradence, {Grant J.} and Nicolas Camper and Qvortrup, {Katrine M.}",
note = "Publisher Copyright: {\textcopyright} 2023 The Royal Society of Chemistry",
year = "2023",
doi = "10.1039/d3cc01596c",
language = "English",
volume = "59",
pages = "7240–7242",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
}