Taichunins A-D, Norditerpenes from Aspergillus taichungensis (IBT 19404)

Hikaru Kato, Momona Sebe, Mika Nagaki, Keisuke Eguchi, Ippei Kagiyama, Yuki Hitora, Jens Christian Frisvad, Robert M. Williams, Sachiko Tsukamoto*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Four new norditerpenes, taichunins A-D (1-4), were isolated from the fungus Aspergillus taichungensis (IBT 19404). Compound 1 has a new carbon framework. The absolute configurations were determined by the calculated ECD spectral method. Compound 1 was cytotoxic against HeLa cells with an IC50 value of 4.5 μM, whereas 2-4 were nontoxic at 50 μM.
Original languageEnglish
JournalJournal of Natural Products
Volume82
Issue number5
Pages (from-to)1377-1381
Number of pages5
ISSN0163-3864
DOIs
Publication statusPublished - 2019

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